deltatrials
Completed PHASE2/PHASE3 INTERVENTIONAL 3-arm NCT01935882

Low Dose Primaquine for Clearance of Gametocytes (LOPRIM)

A Double Blind Randomized Controlled Trial to Assess the Efficacy and Safety of Low Dose Primaquine for Clearance of Gametocytes in Asymptomatic Individuals Infected With P. Falciparum in Burkina Faso

Sponsor: Centre national de recherche et de formation sur le paludisme

Conditions Asymptomatic Malaria Malaria Plasmodium Falciparum
Interventions Artemether-Lumefantrine with a single dose of 0.25mg/kg primaquine Artemether-Lumefantrine with a single dose of 0.4mg/kg primaquine Artemether-lumefantrine combination
Updated 7 times since 2017 Last updated: Sep 1, 2015 Started: Sep 30, 2013 Primary completion: Jul 31, 2015 Completion: Jul 31, 2015
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2/PHASE3 trial investigates Asymptomatic Malaria and Malaria and is currently completed. Centre national de recherche et de formation sur le paludisme leads this study, which shows 7 recorded versions since 2013 — indicating limited longitudinal coverage. Longitudinal tracking of infectious disease trials helps identify durability of treatment effects.

Status Flow

~Jan 2017 – ~Jun 2018 · 17 months · monthly snapshotCompleted~Jun 2018 – ~May 2020 · 23 months · monthly snapshotCompleted~May 2020 – ~Jan 2021 · 8 months · monthly snapshotCompleted~Jan 2021 – ~Mar 2022 · 14 months · monthly snapshotCompleted~Mar 2022 – ~Jul 2024 · 28 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 22 months · monthly snapshotCompleted

Change History

7 versions recorded

  1. Sep 2024 — Present [monthly]

    Completed PHASE2/PHASE3

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2/PHASE3

    Phase: PHASE2_PHASE3 → PHASE2/PHASE3

  3. Mar 2022 — Jul 2024 [monthly]

    Completed PHASE2_PHASE3

  4. Jan 2021 — Mar 2022 [monthly]

    Completed PHASE2_PHASE3

  5. May 2020 — Jan 2021 [monthly]

    Completed PHASE2_PHASE3

▶ Show 2 earlier versions

  1. Jun 2018 — May 2020 [monthly]

    Completed PHASE2_PHASE3

  2. Jan 2017 — Jun 2018 [monthly]

    Completed PHASE2_PHASE3

    First recorded

Sep 2013

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Centre national de recherche et de formation sur le paludisme
  • London School of Hygiene and Tropical Medicine
  • Radboud University Medical Center
Data source: London School of Hygiene and Tropical Medicine

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations