Active Not Recruiting PHASE1/PHASE2 INTERVENTIONAL 1-arm NCT01966367

CD34+ (Non-Malignant) Stem Cell Selection for Patients Receiving Allogeneic Stem Cell Transplantation

CD34+ Stem Cell Selection for Patients Receiving a Matched or Partially Matched Family or Unrelated Adult Donor Allogeneic Stem Cell Transplantation for Non-Malignant Disease

Sponsor: Diane George

Conditions Acquired Immunodeficiency Syndromes Amegakaryocytic Thrombocytopenia Bone Marrow Failure Syndrome Diamond-Blackfan Anemia Familial Hemophagocytic Lymphocytosis Hemoglobinopathies Histiocytic Syndrome Langerhans Cell Histiocytosis (LCH) Lymphohistiocytosis Macrophage Activation Syndrome Primary Immunodeficiency Syndromes Schwachman Diamond Syndrome Severe Aplastic Anemia Severe Congenital Neutropenia Sickle Cell Disease Sickle Cell-beta-thalassemia

Interventions CD34 Stem Cell Selection Therapy

Updated 10 times since 2017 Last updated: Aug 11, 2025 Started: Mar 31, 2013 Primary completion: Feb 28, 2030 Completion: Feb 28, 2030

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT01966367, this PHASE1/PHASE2 trial focuses on Acquired Immunodeficiency Syndromes and Amegakaryocytic Thrombocytopenia and remains ongoing. Sponsored by Diane George, it has been updated 10 times since 2013, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

Change History

10 versions recorded

Sep 2025 — Present [monthly]

Active Not Recruiting PHASE1/PHASE2
Sep 2024 — Sep 2025 [monthly]

Active Not Recruiting PHASE1/PHASE2
Jul 2024 — Sep 2024 [monthly]

Active Not Recruiting PHASE1/PHASE2

Phase: PHASE1_PHASE2 → PHASE1/PHASE2
Jan 2021 — Jul 2024 [monthly]

Active Not Recruiting PHASE1_PHASE2
Jul 2020 — Jan 2021 [monthly]

Active Not Recruiting PHASE1_PHASE2

Status: Recruiting → Active Not Recruiting · Phase: EARLY_PHASE1 → PHASE1_PHASE2

▶ Show 5 earlier versions

Apr 2019 — Jul 2020 [monthly]

Recruiting EARLY_PHASE1
Jun 2018 — Apr 2019 [monthly]

Recruiting EARLY_PHASE1
Aug 2017 — Jun 2018 [monthly]

Recruiting EARLY_PHASE1

Phase: NA → EARLY_PHASE1
Feb 2017 — Aug 2017 [monthly]

Recruiting NA
Jan 2017 — Feb 2017 [monthly]

Recruiting NA

First recorded

Mar 2013

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Diane George

Data source: Columbia University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• New York, United States