deltatrials
Completed PHASE1 INTERVENTIONAL 3-arm NCT01973543

Safety Study of AADC Gene Therapy (VY-AADC01) for Parkinson's Disease (AADC)

An Open-label Safety and Efficacy Study of VY-AADC01 Administered by MRI-Guided Convective Infusion Into the Putamen of Subjects With Parkinson's Disease With Fluctuating Responses to Levodopa

Sponsor: Feinstein Institute for Medical Research

Interventions VY-AADC01
Updated 12 times since 2017 Last updated: Feb 28, 2020 Started: Oct 31, 2013 Primary completion: Jan 24, 2020 Completion: Jan 24, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT01973543, this PHASE1 trial focuses on Parkinson's Disease and remains completed. Sponsored by Feinstein Institute for Medical Research, it has been updated 12 times since 2013, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotRecruiting~Feb 2017 – ~Jul 2017 · 5 months · monthly snapshotActive Not Recruiting~Jul 2017 – ~Jun 2018 · 11 months · monthly snapshotActive Not Recruiting~Jun 2018 – ~Aug 2018 · 2 months · monthly snapshotActive Not Recruiting~Aug 2018 – ~Sep 2018 · 31 days · monthly snapshotActive Not Recruiting~Sep 2018 – ~Jan 2019 · 4 months · monthly snapshotActive Not Recruiting~Jan 2019 – ~Apr 2019 · 3 months · monthly snapshotActive Not Recruiting~Apr 2019 – ~Apr 2020 · 12 months · monthly snapshotActive Not Recruiting~Apr 2020 – ~Jan 2021 · 9 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 22 months · monthly snapshotCompleted

Change History

12 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  3. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE1

  4. Apr 2020 — Jan 2021 [monthly]

    Completed PHASE1

    Status: Active Not RecruitingCompleted

  5. Apr 2019 — Apr 2020 [monthly]

    Active Not Recruiting PHASE1

Show 7 earlier versions
  1. Jan 2019 — Apr 2019 [monthly]

    Active Not Recruiting PHASE1

  2. Sep 2018 — Jan 2019 [monthly]

    Active Not Recruiting PHASE1

  3. Aug 2018 — Sep 2018 [monthly]

    Active Not Recruiting PHASE1

  4. Jun 2018 — Aug 2018 [monthly]

    Active Not Recruiting PHASE1

  5. Jul 2017 — Jun 2018 [monthly]

    Active Not Recruiting PHASE1

  6. Feb 2017 — Jul 2017 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  7. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE1

    First recorded

Oct 2013

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Feinstein Institute for Medical Research
  • Neurocrine Biosciences
  • Oregon Health and Science University
  • University of California, San Francisco
  • Veristat, Inc.
  • Voyager Therapeutics
Data source: Neurocrine Biosciences

For direct contact, visit the study record on ClinicalTrials.gov .