deltatrials
Completed OBSERVATIONAL NCT01976715

Study of People With HIV Infection Who Have High Viral Loads Despite Combination Antiretroviral Therapy

Characterization and Management of Patients With HIV-1 Infection Who Experience Virologic Failure Despite Combination Antiretroviral Therapy

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Updated 60 times since 2017 Last updated: Sep 22, 2025 Started: Feb 11, 2014 Primary completion: Dec 22, 2022 Completion: Dec 22, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This observational or N/A phase trial investigates AIDS Virus and Acquired Immune Deficiency Syndrome Virus and is currently completed. National Institute of Allergy and Infectious Diseases (NIAID) leads this study, which shows 60 recorded versions since 2014 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~May 2017 · 4 months · monthly snapshot~May 2017 – ~Jun 2017 · 31 days · monthly snapshot~Jun 2017 – ~Apr 2018 · 10 months · monthly snapshot~Apr 2018 – ~Jun 2018 · 2 months · monthly snapshot~Jun 2018 – ~Sep 2018 · 3 months · monthly snapshot~Sep 2018 – ~Feb 2019 · 5 months · monthly snapshot~Feb 2019 – ~Mar 2019 · 28 days · monthly snapshot~Mar 2019 – ~May 2019 · 2 months · monthly snapshot~May 2019 – ~Aug 2019 · 3 months · monthly snapshot~Aug 2019 – ~Oct 2019 · 2 months · monthly snapshot~Oct 2019 – ~Jan 2020 · 3 months · monthly snapshot~Jan 2020 – ~Mar 2020 · 2 months · monthly snapshot~Mar 2020 – ~Apr 2020 · 31 days · monthly snapshot~Apr 2020 – ~May 2020 · 30 days · monthly snapshot~May 2020 – ~Jul 2020 · 2 months · monthly snapshot~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshot~Aug 2020 – ~Oct 2020 · 2 months · monthly snapshot~Oct 2020 – ~Dec 2020 · 2 months · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~May 2021 · 4 months · monthly snapshot~May 2021 – ~Oct 2021 · 5 months · monthly snapshot~Oct 2021 – ~Nov 2021 · 31 days · monthly snapshot~Nov 2021 – ~Jan 2022 · 2 months · monthly snapshot~Jan 2022 – ~Feb 2022 · 31 days · monthly snapshot~Feb 2022 – ~Mar 2022 · 28 days · monthly snapshot~Mar 2022 – ~Apr 2022 · 31 days · monthly snapshot~Apr 2022 – ~May 2022 · 30 days · monthly snapshot~May 2022 – ~Jun 2022 · 31 days · monthly snapshot~Jun 2022 – ~Jul 2022 · 30 days · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Nov 2022 · 2 months · monthly snapshot~Nov 2022 – ~Dec 2022 · 30 days · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Feb 2023 · 31 days · monthly snapshot~Feb 2023 – ~Apr 2023 · 59 days · monthly snapshot~Apr 2023 – ~Jun 2023 · 2 months · monthly snapshot~Jun 2023 – ~Sep 2023 · 3 months · monthly snapshot~Sep 2023 – ~Oct 2023 · 30 days · monthly snapshot~Oct 2023 – ~Dec 2023 · 2 months · monthly snapshot~Dec 2023 – ~Jan 2024 · 31 days · monthly snapshot~Jan 2024 – ~Feb 2024 · 31 days · monthly snapshot~Feb 2024 – ~May 2024 · 3 months · monthly snapshot~May 2024 – ~Jun 2024 · 31 days · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Nov 2024 · 31 days · monthly snapshot~Nov 2024 – ~Dec 2024 · 30 days · monthly snapshot~Dec 2024 – ~Jan 2025 · 31 days · monthly snapshot~Jan 2025 – ~Feb 2025 · 31 days · monthly snapshot~Feb 2025 – ~Mar 2025 · 28 days · monthly snapshot~Mar 2025 – ~Apr 2025 · 31 days · monthly snapshot~Apr 2025 – ~May 2025 · 30 days · monthly snapshot~May 2025 – ~Jun 2025 · 31 days · monthly snapshot~Jun 2025 – ~Jul 2025 · 30 days · monthly snapshot~Jul 2025 – ~Aug 2025 · 31 days · monthly snapshot~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – ~Oct 2025 · 30 days · monthly snapshot~Oct 2025 – present · 9 months · monthly snapshot

Change History

60 versions recorded
  1. Oct 2025 — Present [monthly]

    Completed

  2. Sep 2025 — Oct 2025 [monthly]

    Completed

  3. Aug 2025 — Sep 2025 [monthly]

    Completed

  4. Jul 2025 — Aug 2025 [monthly]

    Completed

  5. Jun 2025 — Jul 2025 [monthly]

    Completed

Show 55 earlier versions
  1. May 2025 — Jun 2025 [monthly]

    Completed

  2. Apr 2025 — May 2025 [monthly]

    Completed

  3. Mar 2025 — Apr 2025 [monthly]

    Completed

  4. Feb 2025 — Mar 2025 [monthly]

    Completed

  5. Jan 2025 — Feb 2025 [monthly]

    Completed

  6. Dec 2024 — Jan 2025 [monthly]

    Completed

  7. Nov 2024 — Dec 2024 [monthly]

    Completed

  8. Oct 2024 — Nov 2024 [monthly]

    Completed

  9. Sep 2024 — Oct 2024 [monthly]

    Completed

  10. Aug 2024 — Sep 2024 [monthly]

    Completed

  11. Jul 2024 — Aug 2024 [monthly]

    Completed

  12. Jun 2024 — Jul 2024 [monthly]

    Completed

  13. May 2024 — Jun 2024 [monthly]

    Completed

  14. Feb 2024 — May 2024 [monthly]

    Completed

  15. Jan 2024 — Feb 2024 [monthly]

    Completed

  16. Dec 2023 — Jan 2024 [monthly]

    Completed

  17. Oct 2023 — Dec 2023 [monthly]

    Completed

  18. Sep 2023 — Oct 2023 [monthly]

    Completed

  19. Jun 2023 — Sep 2023 [monthly]

    Completed

  20. Apr 2023 — Jun 2023 [monthly]

    Completed

  21. Feb 2023 — Apr 2023 [monthly]

    Completed

    Status: Active Not RecruitingCompleted

  22. Jan 2023 — Feb 2023 [monthly]

    Active Not Recruiting

  23. Dec 2022 — Jan 2023 [monthly]

    Active Not Recruiting

  24. Nov 2022 — Dec 2022 [monthly]

    Active Not Recruiting

  25. Sep 2022 — Nov 2022 [monthly]

    Active Not Recruiting

  26. Jul 2022 — Sep 2022 [monthly]

    Active Not Recruiting

  27. Jun 2022 — Jul 2022 [monthly]

    Active Not Recruiting

  28. May 2022 — Jun 2022 [monthly]

    Active Not Recruiting

  29. Apr 2022 — May 2022 [monthly]

    Active Not Recruiting

  30. Mar 2022 — Apr 2022 [monthly]

    Active Not Recruiting

    Status: RecruitingActive Not Recruiting

  31. Feb 2022 — Mar 2022 [monthly]

    Recruiting

  32. Jan 2022 — Feb 2022 [monthly]

    Recruiting

  33. Nov 2021 — Jan 2022 [monthly]

    Recruiting

  34. Oct 2021 — Nov 2021 [monthly]

    Recruiting

  35. May 2021 — Oct 2021 [monthly]

    Recruiting

  36. Jan 2021 — May 2021 [monthly]

    Recruiting

  37. Dec 2020 — Jan 2021 [monthly]

    Recruiting

  38. Oct 2020 — Dec 2020 [monthly]

    Recruiting

  39. Aug 2020 — Oct 2020 [monthly]

    Recruiting

  40. Jul 2020 — Aug 2020 [monthly]

    Recruiting

  41. May 2020 — Jul 2020 [monthly]

    Recruiting

  42. Apr 2020 — May 2020 [monthly]

    Recruiting

  43. Mar 2020 — Apr 2020 [monthly]

    Recruiting

  44. Jan 2020 — Mar 2020 [monthly]

    Recruiting

  45. Oct 2019 — Jan 2020 [monthly]

    Recruiting

  46. Aug 2019 — Oct 2019 [monthly]

    Recruiting

  47. May 2019 — Aug 2019 [monthly]

    Recruiting

  48. Mar 2019 — May 2019 [monthly]

    Recruiting

  49. Feb 2019 — Mar 2019 [monthly]

    Recruiting

  50. Sep 2018 — Feb 2019 [monthly]

    Recruiting

  51. Jun 2018 — Sep 2018 [monthly]

    Recruiting

  52. Apr 2018 — Jun 2018 [monthly]

    Recruiting

    Phase: NANone

  53. Jun 2017 — Apr 2018 [monthly]

    Recruiting NA

  54. May 2017 — Jun 2017 [monthly]

    Recruiting NA

  55. Jan 2017 — May 2017 [monthly]

    Recruiting NA

    First recorded

Feb 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Institute of Allergy and Infectious Diseases (NIAID)
Data source: National Institutes of Health Clinical Center (CC)

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations