deltatrials
Completed PHASE1/PHASE2 INTERVENTIONAL 1-arm NCT02039336

Dacomitinib Plus PD-0325901 in Advanced KRAS Mutant NSCLC (M13DAP)

Phase I/II Study With the Combination of Dacomitinib and PD-0325901 in Metastatic KRAS Mutation Positive Non-small Cell Lung Cancer

Sponsor: Pfizer

Conditions Colorectal Cancer
Interventions Dacomitinib Docetaxel PD-0325901
Updated 10 times since 2017 Last updated: Jul 2, 2025 Started: Apr 2, 2014 Primary completion: Aug 7, 2018 Completion: Aug 7, 2018
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02039336, this PHASE1/PHASE2 trial focuses on Colorectal Cancer and remains completed. Sponsored by Pfizer, it has been updated 10 times since 2014, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2017 – ~Aug 2017 · 7 months · monthly snapshotRecruiting~Aug 2017 – ~Dec 2017 · 4 months · monthly snapshotRecruiting~Dec 2017 – ~Jun 2018 · 6 months · monthly snapshotRecruiting~Jun 2018 – ~Sep 2018 · 3 months · monthly snapshotRecruiting~Sep 2018 – ~Sep 2020 · 24 months · monthly snapshotRecruiting~Sep 2020 – ~Jan 2021 · 4 months · monthly snapshotUnknown Status~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotUnknown Status~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotUnknown~Sep 2024 – ~Aug 2025 · 11 months · monthly snapshotUnknown~Aug 2025 – present · 12 months · monthly snapshotCompleted

Change History

10 versions recorded

  1. Aug 2025 — Present [monthly]

    Completed PHASE1/PHASE2

    Status: Unknown → Completed

  2. Sep 2024 — Aug 2025 [monthly]

    Unknown PHASE1/PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Unknown PHASE1/PHASE2

    Status: Unknown Status → Unknown · Phase: PHASE1_PHASE2 → PHASE1/PHASE2

  4. Jan 2021 — Jul 2024 [monthly]

    Unknown Status PHASE1_PHASE2

  5. Sep 2020 — Jan 2021 [monthly]

    Unknown Status PHASE1_PHASE2

    Status: Recruiting → Unknown Status

▶ Show 5 earlier versions

  1. Sep 2018 — Sep 2020 [monthly]

    Recruiting PHASE1_PHASE2

  2. Jun 2018 — Sep 2018 [monthly]

    Recruiting PHASE1_PHASE2

  3. Dec 2017 — Jun 2018 [monthly]

    Recruiting PHASE1_PHASE2

  4. Aug 2017 — Dec 2017 [monthly]

    Recruiting PHASE1_PHASE2

  5. Jan 2017 — Aug 2017 [monthly]

    Recruiting PHASE1_PHASE2

    First recorded

Apr 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Pfizer
  • The Netherlands Cancer Institute
Data source: The Netherlands Cancer Institute

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations