deltatrials
Completed PHASE1 INTERVENTIONAL 2-arm NCT02049593

PARP Inhibitor BMN-673 and Temozolomide or Irinotecan Hydrochloride in Treating Patients With Locally Advanced or Metastatic Solid Tumors

Phase I Trial of BMN 673 and Selected Cytotoxics in Patients With Advanced Solid Tumors

Sponsor: BioMarin Pharmaceutical

Updated 11 times since 2017 Last updated: Sep 22, 2022 Started: Jun 12, 2014 Primary completion: Oct 7, 2019 Completion: Oct 7, 2019
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02049593, this PHASE1 trial focuses on Metastatic Cancer and Unspecified Adult Solid Tumor and remains completed. Sponsored by BioMarin Pharmaceutical, it has been updated 11 times since 2014, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotActive Not Recruiting~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshotActive Not Recruiting~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshotActive Not Recruiting~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshotActive Not Recruiting~Aug 2018 – ~Sep 2019 · 13 months · monthly snapshotActive Not Recruiting~Sep 2019 – ~Dec 2019 · 3 months · monthly snapshotActive Not Recruiting~Dec 2019 – ~Jan 2021 · 13 months · monthly snapshotCompleted~Jan 2021 – ~Sep 2022 · 20 months · monthly snapshotCompleted~Sep 2022 – ~Jul 2024 · 22 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 20 months · monthly snapshotCompleted

Change History

11 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  3. Sep 2022 — Jul 2024 [monthly]

    Completed PHASE1

  4. Jan 2021 — Sep 2022 [monthly]

    Completed PHASE1

  5. Dec 2019 — Jan 2021 [monthly]

    Completed PHASE1

    Status: Active Not RecruitingCompleted

Show 6 earlier versions
  1. Sep 2019 — Dec 2019 [monthly]

    Active Not Recruiting PHASE1

  2. Aug 2018 — Sep 2019 [monthly]

    Active Not Recruiting PHASE1

  3. Jul 2018 — Aug 2018 [monthly]

    Active Not Recruiting PHASE1

  4. Jun 2018 — Jul 2018 [monthly]

    Active Not Recruiting PHASE1

  5. Feb 2017 — Jun 2018 [monthly]

    Active Not Recruiting PHASE1

  6. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE1

    First recorded

Jun 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • BioMarin Pharmaceutical
  • Jonsson Comprehensive Cancer Center
  • Medivation, Inc.
  • Translational Research in Oncology
Data source: Jonsson Comprehensive Cancer Center

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations