deltatrials
Completed NA INTERVENTIONAL 1-arm NCT02072486

Sorafenib Tosylate in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery

Granzyme B Production as a Biomarker for the Immunomodulatory Activity of Sorafenib in HCC

Sponsor: National Comprehensive Cancer Network

Conditions Advanced Adult Hepatocellular Carcinoma Localized Non-Resectable Adult Hepatocellular Carcinoma Stage III Childhood Hepatocellular Carcinoma Stage IIIA Hepatocellular Carcinoma Stage IIIB Hepatocellular Carcinoma Stage IIIC Hepatocellular Carcinoma Stage IV Childhood Hepatocellular Carcinoma Stage IVA Hepatocellular Carcinoma Stage IVB Hepatocellular Carcinoma
Interventions Laboratory Biomarker Analysis Sorafenib Tosylate
Updated 21 times since 2017 Last updated: Jul 20, 2022 Started: Nov 18, 2013 Primary completion: Jul 19, 2019 Completion: Jul 19, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02072486, this NA trial focuses on Advanced Adult Hepatocellular Carcinoma and Localized Non-Resectable Adult Hepatocellular Carcinoma and remains completed. Sponsored by National Comprehensive Cancer Network, it has been updated 21 times since 2013, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Aug 2017 · 6 months · monthly snapshot~Aug 2017 – ~Jun 2018 · 10 months · monthly snapshot~Jun 2018 – ~Aug 2018 · 2 months · monthly snapshot~Aug 2018 – ~Sep 2018 · 31 days · monthly snapshot~Sep 2018 – ~Nov 2018 · 2 months · monthly snapshot~Nov 2018 – ~Jan 2019 · 2 months · monthly snapshot~Jan 2019 – ~Apr 2019 · 3 months · monthly snapshot~Apr 2019 – ~May 2019 · 30 days · monthly snapshot~May 2019 – ~Jun 2019 · 31 days · monthly snapshot~Jun 2019 – ~Aug 2019 · 2 months · monthly snapshot~Aug 2019 – ~Nov 2019 · 3 months · monthly snapshot~Nov 2019 – ~Jan 2020 · 2 months · monthly snapshot~Jan 2020 – ~Mar 2020 · 2 months · monthly snapshot~Mar 2020 – ~Jul 2020 · 4 months · monthly snapshot~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshot~Aug 2020 – ~Jan 2021 · 5 months · monthly snapshot~Jan 2021 – ~Sep 2022 · 20 months · monthly snapshot~Sep 2022 – ~Jul 2024 · 22 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 22 months · monthly snapshot

Change History

21 versions recorded

  1. Sep 2024 — Present [monthly]

    Completed NA

  2. Jul 2024 — Sep 2024 [monthly]

    Completed NA

  3. Sep 2022 — Jul 2024 [monthly]

    Completed NA

  4. Jan 2021 — Sep 2022 [monthly]

    Completed NA

  5. Aug 2020 — Jan 2021 [monthly]

    Completed NA

    Status: Active Not Recruiting → Completed

▶ Show 16 earlier versions

  1. Jul 2020 — Aug 2020 [monthly]

    Active Not Recruiting NA

  2. Mar 2020 — Jul 2020 [monthly]

    Active Not Recruiting NA

  3. Jan 2020 — Mar 2020 [monthly]

    Active Not Recruiting NA

  4. Nov 2019 — Jan 2020 [monthly]

    Active Not Recruiting NA

  5. Aug 2019 — Nov 2019 [monthly]

    Active Not Recruiting NA

  6. Jun 2019 — Aug 2019 [monthly]

    Active Not Recruiting NA

  7. May 2019 — Jun 2019 [monthly]

    Active Not Recruiting NA

  8. Apr 2019 — May 2019 [monthly]

    Active Not Recruiting NA

  9. Jan 2019 — Apr 2019 [monthly]

    Active Not Recruiting NA

  10. Nov 2018 — Jan 2019 [monthly]

    Active Not Recruiting NA

  11. Sep 2018 — Nov 2018 [monthly]

    Active Not Recruiting NA

  12. Aug 2018 — Sep 2018 [monthly]

    Active Not Recruiting NA

  13. Jun 2018 — Aug 2018 [monthly]

    Active Not Recruiting NA

  14. Aug 2017 — Jun 2018 [monthly]

    Active Not Recruiting NA

    Status: Recruiting → Active Not Recruiting

  15. Feb 2017 — Aug 2017 [monthly]

    Recruiting NA

  16. Jan 2017 — Feb 2017 [monthly]

    Recruiting NA

    First recorded

Nov 2013

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Comprehensive Cancer Network
  • Roswell Park Cancer Institute
Data source: Roswell Park Cancer Institute

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations