deltatrials
Completed PHASE1/PHASE2 INTERVENTIONAL 2-arm NCT02092116

Safety and Efficacy of Romidepsin and the Therapeutic Vaccine Vacc-4x for Reduction of the Latent HIV-1 Reservoir (REDUC)

An Open Phase I/IIa Study to Evaluate the Safety and Effect of Therapeutic HIV-1 Immunization Using Vacc-4x + rhuGM-CSF and HIV-1 Reactivation Using Romidepsin on the Viral Reservoir in Virologically Suppressed HIV-1 Infected Adults on cART

Sponsor: Bionor Immuno AS

Updated 8 times since 2017 Last updated: Jan 11, 2017 Started: Mar 31, 2014 Primary completion: Aug 31, 2015 Completion: Dec 31, 2015
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1/PHASE2 trial investigates HIV I Infection and is currently completed. Bionor Immuno AS leads this study, which shows 8 recorded versions since 2014 — indicating limited longitudinal coverage. Longitudinal tracking of infectious disease trials helps identify durability of treatment effects.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotUnknown Status~Feb 2017 – ~May 2017 · 3 months · monthly snapshotUnknown Status~May 2017 – ~Jun 2018 · 13 months · monthly snapshotCompleted~Jun 2018 – ~Sep 2020 · 27 months · monthly snapshotCompleted~Sep 2020 – ~Jan 2021 · 4 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 22 months · monthly snapshotCompleted

Change History

8 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE1/PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

  3. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE1_PHASE2

  4. Sep 2020 — Jan 2021 [monthly]

    Completed PHASE1_PHASE2

  5. Jun 2018 — Sep 2020 [monthly]

    Completed PHASE1_PHASE2

Show 3 earlier versions
  1. May 2017 — Jun 2018 [monthly]

    Completed PHASE1_PHASE2

    Status: Unknown StatusCompleted

  2. Feb 2017 — May 2017 [monthly]

    Unknown Status PHASE1_PHASE2

  3. Jan 2017 — Feb 2017 [monthly]

    Unknown Status PHASE1_PHASE2

    First recorded

Mar 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Bionor Immuno AS
  • Celgene Corporation
Data source: Bionor Immuno AS

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations