deltatrials
Completed PHASE2 INTERVENTIONAL 1-arm NCT02093533

Eculizumab in Primary MPGN (EAGLE)

EVALUATING THE MORPHOFUNCTIONAL EFFECTS OF ECULIZUMAB THERAPY IN PRIMARY MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS: A PILOT, SINGLE ARM STUDY IN TEN PATIENTS WITH PERSISTENT HEAVY PROTEINURIA

Sponsor: Alexion Pharma Italy s.r.l.

Interventions Eculizumab
Updated 8 times since 2017 Last updated: Jan 15, 2018 Started: Mar 31, 2014 Primary completion: Dec 31, 2017 Completion: Dec 31, 2017
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Membranoproliferative Glomerulonephritis, this trial is completed. The trial is conducted by Alexion Pharma Italy s.r.l. and has accumulated 8 data snapshots since 2014. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Jan 2017 – ~Jun 2017 · 5 months · monthly snapshotActive Not Recruiting~Jun 2017 – ~Feb 2018 · 8 months · monthly snapshotActive Not Recruiting~Feb 2018 – ~Jun 2018 · 4 months · monthly snapshotCompleted~Jun 2018 – ~Jan 2021 · 31 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 12 months · monthly snapshotCompleted

Change History

8 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  4. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE2

  5. Jun 2018 — Jan 2021 [monthly]

    Completed PHASE2

Show 3 earlier versions
  1. Feb 2018 — Jun 2018 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

  2. Jun 2017 — Feb 2018 [monthly]

    Active Not Recruiting PHASE2

  3. Jan 2017 — Jun 2017 [monthly]

    Active Not Recruiting PHASE2

    First recorded

Mar 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Alexion Pharma Italy s.r.l.
  • Mario Negri Institute for Pharmacological Research
Data source: Mario Negri Institute for Pharmacological Research

For direct contact, visit the study record on ClinicalTrials.gov .