deltatrials
Terminated PHASE2 INTERVENTIONAL 2-arm NCT02096588

Detection and Prevention of Anthracycline-Related Cardiac Toxicity With Concurrent Simvastatin

Sponsor: Avon Foundation

Conditions Breast Cancer Stage I Breast Cancer Stage II Breast Cancer Stage III Breast Cancer
Interventions Doxorubicin/cyclophosphamide Simvastatin
Updated 17 times since 2017 Last updated: Jun 12, 2024 Started: May 20, 2014 Primary completion: Apr 25, 2017 Completion: Jul 26, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

The Principal Investigator left Johns Hopkins

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Other Breast Cancer trials with similar outcome

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Listed as NCT02096588, this PHASE2 trial focuses on Breast Cancer and Stage I Breast Cancer and remains terminated or withdrawn. Sponsored by Avon Foundation, it has been updated 17 times since 2014, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Oct 2017 · 8 months · monthly snapshot~Oct 2017 – ~May 2018 · 7 months · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Jul 2019 · 13 months · monthly snapshot~Jul 2019 – ~Jul 2020 · 12 months · monthly snapshot~Jul 2020 – ~Jan 2021 · 6 months · monthly snapshot~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshot~Sep 2021 – ~Jul 2022 · 10 months · monthly snapshot~Jul 2022 – ~Apr 2023 · 9 months · monthly snapshot~Apr 2023 – ~Aug 2023 · 4 months · monthly snapshot~Aug 2023 – ~Apr 2024 · 8 months · monthly snapshot~Apr 2024 – ~Jul 2024 · 3 months · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

17 versions recorded

  1. Sep 2025 — Present [monthly]

    Terminated PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE2

  3. Aug 2024 — Sep 2024 [monthly]

    Terminated PHASE2

  4. Jul 2024 — Aug 2024 [monthly]

    Terminated PHASE2

  5. Apr 2024 — Jul 2024 [monthly]

    Terminated PHASE2

    Status: Active Not Recruiting → Terminated

▶ Show 12 earlier versions

  1. Aug 2023 — Apr 2024 [monthly]

    Active Not Recruiting PHASE2

  2. Apr 2023 — Aug 2023 [monthly]

    Active Not Recruiting PHASE2

  3. Jul 2022 — Apr 2023 [monthly]

    Active Not Recruiting PHASE2

  4. Sep 2021 — Jul 2022 [monthly]

    Active Not Recruiting PHASE2

  5. Jan 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE2

  6. Jul 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE2

  7. Jul 2019 — Jul 2020 [monthly]

    Active Not Recruiting PHASE2

  8. Jun 2018 — Jul 2019 [monthly]

    Active Not Recruiting PHASE2

  9. May 2018 — Jun 2018 [monthly]

    Active Not Recruiting PHASE2

  10. Oct 2017 — May 2018 [monthly]

    Active Not Recruiting PHASE2

    Status: Recruiting → Active Not Recruiting

  11. Feb 2017 — Oct 2017 [monthly]

    Recruiting PHASE2

  12. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE2

    First recorded

May 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Avon Foundation
  • Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Data source: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations