Completed PHASE2 INTERVENTIONAL 2-arm NCT02098629

Concomitant Milrinone and Esmolol Treatment in Patients with Acute Myocardial Infarction (COMET-AMI)

Sponsor: National University Hospital, Singapore

Conditions Myocardial Reperfusion Injury

Interventions Esmolol Milrinone Saline Infusion

Updated 8 times since 2017 Last updated: Jan 6, 2025 Started: May 31, 2015 Primary completion: Mar 31, 2023 Completion: Dec 31, 2024

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Myocardial Reperfusion Injury and is currently completed. National University Hospital, Singapore leads this study, which shows 8 recorded versions since 2015 — indicating limited longitudinal coverage. Heart and vascular conditions benefit from the kind of long-term tracking this trial provides.

Status Flow

Change History

8 versions recorded

Mar 2026 — Present [monthly]

Completed PHASE2
Feb 2025 — Mar 2026 [monthly]

Completed PHASE2

Status: Withdrawn → Completed · Phase: PHASE1/PHASE2 → PHASE2
Sep 2024 — Feb 2025 [monthly]

Withdrawn PHASE1/PHASE2
Jul 2024 — Sep 2024 [monthly]

Withdrawn PHASE1/PHASE2

Phase: PHASE1_PHASE2 → PHASE1/PHASE2
Jan 2021 — Jul 2024 [monthly]

Withdrawn PHASE1_PHASE2

▶ Show 3 earlier versions

Jun 2018 — Jan 2021 [monthly]

Withdrawn PHASE1_PHASE2
Oct 2017 — Jun 2018 [monthly]

Withdrawn PHASE1_PHASE2

Status: Recruiting → Withdrawn
Jan 2017 — Oct 2017 [monthly]

Recruiting PHASE1_PHASE2

First recorded

May 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

National University Hospital, Singapore
Shantou University Medical College

Data source: Shantou University Medical College

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Singapore, Singapore