deltatrials
Completed PHASE2 INTERVENTIONAL 1-arm NCT02113033

VAgal Nerve Stimulation: safeGUARDing Heart Failure Patients (VANGUARD)

Sponsor: LivaNova

Conditions Heart Failure With Reduced Ejection Fraction
Interventions Equilia® Vagal Nerve Stimulation
Updated 8 times since 2017 Last updated: Mar 12, 2018 Started: Oct 7, 2014 Primary completion: Feb 22, 2016 Completion: Sep 20, 2016
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Heart Failure With Reduced Ejection Fraction, this trial is completed. The trial is conducted by LivaNova and has accumulated 8 data snapshots since 2014. Cardiovascular trials of this type often inform treatment guidelines for long-term patient management.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotActive Not Recruiting~Feb 2017 – ~Mar 2018 · 13 months · monthly snapshotActive Not Recruiting~Mar 2018 – ~Jun 2018 · 3 months · monthly snapshotCompleted~Jun 2018 – ~Jan 2021 · 31 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 10 months · monthly snapshotCompleted

Change History

8 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  4. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE2

  5. Jun 2018 — Jan 2021 [monthly]

    Completed PHASE2

▶ Show 3 earlier versions

  1. Mar 2018 — Jun 2018 [monthly]

    Completed PHASE2

    Status: Active Not Recruiting → Completed

  2. Feb 2017 — Mar 2018 [monthly]

    Active Not Recruiting PHASE2

  3. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE2

    First recorded

Oct 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • LivaNova
Data source: LivaNova

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations