deltatrials
Completed PHASE2 INTERVENTIONAL 2-arm NCT02120781

Controlled Study to Evaluate the Safety and Efficacy of Azficel-T for Vocal Fold Scarring and Age-Related Dysphonia

A Phase II, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Azficel-T for the Treatment of Vocal Fold Scarring and Age-Related Dysphonia

Sponsor: Castle Creek Biosciences, LLC.

Conditions Age-related Dysphonia Dysphonia Resulting From Vocal Fold Scarring
Interventions Azficel-T (autologous fibroblasts) Placebo
Updated 8 times since 2017 Last updated: May 10, 2021 Started: Mar 31, 2014 Primary completion: Apr 30, 2016 Completion: Dec 21, 2016
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Age-related Dysphonia and Dysphonia Resulting From Vocal Fold Scarring and is currently completed. Castle Creek Biosciences, LLC. leads this study, which shows 8 recorded versions since 2014 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotActive Not Recruiting~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshotCompleted~Jun 2018 – ~Jan 2021 · 31 months · monthly snapshotCompleted~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshotCompleted~Feb 2021 – ~Sep 2021 · 7 months · monthly snapshotCompleted~Sep 2021 – ~Jul 2024 · 34 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 24 months · monthly snapshotCompleted

Change History

8 versions recorded

  1. Sep 2024 — Present [monthly]

    Completed PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  3. Sep 2021 — Jul 2024 [monthly]

    Completed PHASE2

  4. Feb 2021 — Sep 2021 [monthly]

    Completed PHASE2

  5. Jan 2021 — Feb 2021 [monthly]

    Completed PHASE2

▶ Show 3 earlier versions

  1. Jun 2018 — Jan 2021 [monthly]

    Completed PHASE2

  2. Feb 2017 — Jun 2018 [monthly]

    Completed PHASE2

    Status: Active Not Recruiting → Completed

  3. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE2

    First recorded

Mar 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Castle Creek Biosciences, LLC.
Data source: Castle Creek Biosciences, LLC.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations