deltatrials
Completed PHASE1 INTERVENTIONAL 4-arm NCT02124941

Glutamate-Glutamine Cycling (VCYC) During Cocaine Abstinence Using 1H-MRS

Sponsor: National Institute on Drug Abuse (NIDA)

Conditions Cocaine Dependence Healthy
Interventions 1H MRS N-acetyl cysteine [11C]APP311 PET scan [18F]FDG PET scan
Updated 18 times since 2017 Last updated: Jul 5, 2023 Started: Feb 28, 2014 Primary completion: Aug 14, 2022 Completion: Aug 14, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02124941, this PHASE1 trial focuses on Cocaine Dependence and Healthy and remains completed. Sponsored by National Institute on Drug Abuse (NIDA), it has been updated 18 times since 2014, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Jul 2017 · 6 months · monthly snapshot~Jul 2017 – ~Jun 2018 · 11 months · monthly snapshot~Jun 2018 – ~Aug 2018 · 2 months · monthly snapshot~Aug 2018 – ~Feb 2019 · 6 months · monthly snapshot~Feb 2019 – ~Aug 2019 · 6 months · monthly snapshot~Aug 2019 – ~Jan 2020 · 5 months · monthly snapshot~Jan 2020 – ~Apr 2020 · 3 months · monthly snapshot~Apr 2020 – ~May 2020 · 30 days · monthly snapshot~May 2020 – ~Oct 2020 · 5 months · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~Jun 2022 · 15 months · monthly snapshot~Jun 2022 – ~Mar 2023 · 9 months · monthly snapshot~Mar 2023 – ~Aug 2023 · 5 months · monthly snapshot~Aug 2023 – ~Jul 2024 · 11 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 23 months · monthly snapshot

Change History

18 versions recorded

  1. Sep 2024 — Present [monthly]

    Completed PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  3. Aug 2023 — Jul 2024 [monthly]

    Completed PHASE1

  4. Mar 2023 — Aug 2023 [monthly]

    Completed PHASE1

    Status: Active Not Recruiting → Completed

  5. Jun 2022 — Mar 2023 [monthly]

    Active Not Recruiting PHASE1

▶ Show 13 earlier versions

  1. Mar 2021 — Jun 2022 [monthly]

    Active Not Recruiting PHASE1

  2. Jan 2021 — Mar 2021 [monthly]

    Active Not Recruiting PHASE1

  3. Nov 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE1

  4. Oct 2020 — Nov 2020 [monthly]

    Active Not Recruiting PHASE1

  5. May 2020 — Oct 2020 [monthly]

    Active Not Recruiting PHASE1

    Status: Recruiting → Active Not Recruiting

  6. Apr 2020 — May 2020 [monthly]

    Recruiting PHASE1

  7. Jan 2020 — Apr 2020 [monthly]

    Recruiting PHASE1

  8. Aug 2019 — Jan 2020 [monthly]

    Recruiting PHASE1

  9. Feb 2019 — Aug 2019 [monthly]

    Recruiting PHASE1

  10. Aug 2018 — Feb 2019 [monthly]

    Recruiting PHASE1

  11. Jun 2018 — Aug 2018 [monthly]

    Recruiting PHASE1

  12. Jul 2017 — Jun 2018 [monthly]

    Recruiting PHASE1

  13. Jan 2017 — Jul 2017 [monthly]

    Recruiting PHASE1

    First recorded

Feb 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Institute on Drug Abuse (NIDA)
  • Yale University
Data source: Yale University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations