deltatrials
Completed PHASE2 INTERVENTIONAL 2-arm NCT02147028

Hippocampal Sparing Whole Brain Radiotherapy vs Conventional Whole Brain Radiotherapy in Patients With Brain Metastases (HIPPO)

A Randomized Phase II Trial of Hippocampal Sparing Versus Conventional Whole Brain Radiotherapy After Surgical Resection or Radiosurgery in Favourable Prognosis Patients With 1-10 Brain Metastases

Sponsor: Cancer Research UK

Updated 10 times since 2017 Last updated: Feb 24, 2021 Started: Aug 3, 2016 Primary completion: Jun 30, 2018 Completion: Feb 16, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Brain Metastases and is currently completed. Cancer Research UK leads this study, which shows 10 recorded versions since 2016 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotNot Yet Recruiting~Feb 2017 – ~May 2018 · 15 months · monthly snapshotRecruiting~May 2018 – ~Jun 2018 · 31 days · monthly snapshotActive Not Recruiting~Jun 2018 – ~Nov 2018 · 5 months · monthly snapshotActive Not Recruiting~Nov 2018 – ~Nov 2020 · 24 months · monthly snapshotActive Not Recruiting~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshotUnknown Status~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshotUnknown Status~Mar 2021 – ~Jul 2024 · 40 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 23 months · monthly snapshotCompleted

Change History

10 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  3. Mar 2021 — Jul 2024 [monthly]

    Completed PHASE2

    Status: Unknown StatusCompleted

  4. Jan 2021 — Mar 2021 [monthly]

    Unknown Status PHASE2

  5. Nov 2020 — Jan 2021 [monthly]

    Unknown Status PHASE2

    Status: Active Not RecruitingUnknown Status

Show 5 earlier versions
  1. Nov 2018 — Nov 2020 [monthly]

    Active Not Recruiting PHASE2

  2. Jun 2018 — Nov 2018 [monthly]

    Active Not Recruiting PHASE2

  3. May 2018 — Jun 2018 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  4. Feb 2017 — May 2018 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  5. Jan 2017 — Feb 2017 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Aug 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Cancer Research UK
  • The Brain Tumour Charity
  • University College, London
Data source: University College, London

For direct contact, visit the study record on ClinicalTrials.gov .