deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT02166476

Efficacy/Safety of Meropenem-Vaborbactam Compared to Piperacillin-Tazobactam in Adults With cUTI and AP

Phase III, Randomized, Double-Blind, Study Evaluating Efficacy/Safety/Tolerability of Meropenem-Vaborbactam Compared to Piperacillin/Tazobactam in Adult Patients With Complicated Urinary Tract Infections, Including Acute Pyelonephritis

Sponsor: Department of Health and Human Services

Updated 9 times since 2017 Last updated: May 11, 2018 Started: Nov 20, 2014 Primary completion: Apr 28, 2016 Completion: Apr 28, 2016
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02166476, this PHASE3 trial focuses on Acute Pyelonephritis and Urinary Tract Infection Complicated and remains completed. Sponsored by Department of Health and Human Services, it has been updated 9 times since 2014, reflecting limited change activity. This study is part of the global effort to build evidence for infectious disease interventions.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotCompleted~Feb 2017 – ~Nov 2017 · 9 months · monthly snapshotCompleted~Nov 2017 – ~Jun 2018 · 7 months · monthly snapshotCompleted~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshotCompleted~Jul 2018 – ~Jan 2021 · 30 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 10 months · monthly snapshotCompleted

Change History

9 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE3

  5. Jul 2018 — Jan 2021 [monthly]

    Completed PHASE3

Show 4 earlier versions
  1. Jun 2018 — Jul 2018 [monthly]

    Completed PHASE3

  2. Nov 2017 — Jun 2018 [monthly]

    Completed PHASE3

  3. Feb 2017 — Nov 2017 [monthly]

    Completed PHASE3

  4. Jan 2017 — Feb 2017 [monthly]

    Completed PHASE3

    First recorded

Nov 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Department of Health and Human Services
  • Melinta Therapeutics, Inc.
Data source: Melinta Therapeutics, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .