deltatrials
Completed PHASE2 INTERVENTIONAL 4-arm NCT02187991

Study to Compare Alisertib With Paclitaxel vs. Paclitaxel Alone in Metastatic or Locally Recurrent Breast Cancer

A Phase II, Multicenter, Randomized, Parallel Group Study to Compare Alisertib in Combination With Paclitaxel vs. Paclitaxel Alone in Patients With Metastatic or Locally Recurrent Breast Cancer

Sponsor: Millennium Pharmaceuticals, Inc.

Updated 16 times since 2017 Last updated: Sep 16, 2024 Started: Feb 12, 2015 Primary completion: Apr 11, 2024 Completion: Aug 1, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Breast Cancer and Breast Carcinoma, this trial is completed. The trial is conducted by Millennium Pharmaceuticals, Inc. and has accumulated 16 data snapshots since 2015. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Jan 2019 · 6 months · monthly snapshot~Jan 2019 – ~Nov 2019 · 10 months · monthly snapshot~Nov 2019 – ~Sep 2020 · 10 months · monthly snapshot~Sep 2020 – ~Jan 2021 · 4 months · monthly snapshot~Jan 2021 – ~Jan 2022 · 12 months · monthly snapshot~Jan 2022 – ~Jun 2022 · 5 months · monthly snapshot~Jun 2022 – ~Dec 2022 · 6 months · monthly snapshot~Dec 2022 – ~Sep 2023 · 9 months · monthly snapshot~Sep 2023 – ~Jul 2024 · 10 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Nov 2024 · 2 months · monthly snapshot~Nov 2024 – ~Sep 2025 · 10 months · monthly snapshot~Sep 2025 – present · 12 months · monthly snapshot

Change History

16 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Nov 2024 — Sep 2025 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

  3. Sep 2024 — Nov 2024 [monthly]

    Active Not Recruiting PHASE2

  4. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE2

  5. Sep 2023 — Jul 2024 [monthly]

    Active Not Recruiting PHASE2

Show 11 earlier versions
  1. Dec 2022 — Sep 2023 [monthly]

    Active Not Recruiting PHASE2

  2. Jun 2022 — Dec 2022 [monthly]

    Active Not Recruiting PHASE2

  3. Jan 2022 — Jun 2022 [monthly]

    Active Not Recruiting PHASE2

  4. Jan 2021 — Jan 2022 [monthly]

    Active Not Recruiting PHASE2

  5. Sep 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE2

  6. Nov 2019 — Sep 2020 [monthly]

    Active Not Recruiting PHASE2

  7. Jan 2019 — Nov 2019 [monthly]

    Active Not Recruiting PHASE2

  8. Jul 2018 — Jan 2019 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  9. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE2

  10. Feb 2017 — Jun 2018 [monthly]

    Recruiting PHASE2

  11. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE2

    First recorded

Feb 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Millennium Pharmaceuticals, Inc.
  • US Oncology Research
Data source: US Oncology Research

For direct contact, visit the study record on ClinicalTrials.gov .