Completed PHASE1/PHASE2 INTERVENTIONAL 2-arm NCT02203968

Fibrinogen in the Initial Resuscitation of Severe Trauma (FiiRST) (FiiRST)

Fibrinogen in the Initial Resuscitation of Severe Trauma (FiiRST): a Randomized Feasibility Trial

Sponsor: Sunnybrook Health Sciences Centre

Conditions Bleeding Coagulopathy Haemorrhage Injury Trauma

Interventions Fibrinogen concentrate Placebo Comparator

Updated 5 times since 2017 Last updated: Apr 13, 2016 Started: Oct 31, 2014 Primary completion: Dec 31, 2015 Completion: Dec 31, 2015

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1/PHASE2 trial investigates Bleeding and Coagulopathy and is currently completed. Sunnybrook Health Sciences Centre leads this study, which shows 5 recorded versions since 2014 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

Change History

5 versions recorded

Sep 2024 — Present [monthly]

Completed PHASE1/PHASE2
Jul 2024 — Sep 2024 [monthly]

Completed PHASE1/PHASE2

Phase: PHASE1_PHASE2 → PHASE1/PHASE2
Jan 2021 — Jul 2024 [monthly]

Completed PHASE1_PHASE2
Jun 2018 — Jan 2021 [monthly]

Completed PHASE1_PHASE2
Jan 2017 — Jun 2018 [monthly]

Completed PHASE1_PHASE2

First recorded

Oct 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Sunnybrook Health Sciences Centre

Data source: Sunnybrook Health Sciences Centre

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Toronto, Canada