Completed PHASE1 INTERVENTIONAL 4-arm NCT02224664

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PF-06649751 in Parkinson's Disease

A Phase 1b, 2-period, Open Label, Multicenter, Dose Escalation Study To Evaluate The Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Of Pf-06649751 In Subjects With Parkinson's Disease And Motor Fluctuations

Sponsor: Pfizer

Conditions Parkinson's Disease

Interventions PF-06649751

Updated 9 times since 2017 Last updated: Feb 3, 2017 Started: Oct 31, 2014 Primary completion: Mar 31, 2016 Completion: Mar 31, 2016

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02224664, this PHASE1 trial focuses on Parkinson's Disease and remains completed. Sponsored by Pfizer, it has been updated 9 times since 2014, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

Change History

9 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE1
Sep 2024 — Sep 2025 [monthly]

Completed PHASE1
Jul 2024 — Sep 2024 [monthly]

Completed PHASE1
Jan 2021 — Jul 2024 [monthly]

Completed PHASE1
Sep 2020 — Jan 2021 [monthly]

Completed PHASE1

▶ Show 4 earlier versions

Jun 2018 — Sep 2020 [monthly]

Completed PHASE1
May 2017 — Jun 2018 [monthly]

Completed PHASE1
Feb 2017 — May 2017 [monthly]

Completed PHASE1
Jan 2017 — Feb 2017 [monthly]

Completed PHASE1

First recorded

Oct 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Pfizer

Data source: Pfizer

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Atlanta, United States , Boston, United States , Brussels, Belgium , Dallas, United States , Englewood, United States , Farmington Hills, United States , Fountain Valley, United States , Hallandale, United States , Lakewood, United States , Long Beach, United States and 4 more locations