deltatrials
Completed PHASE4 INTERVENTIONAL 1-arm NCT02246218

A Study of the Safety, Efficacy and Pharmacokinetics of Glycerol Phenylbutyrate in Pediatric Subjects Under 2 Years of Age With Urea Cycle Disorders

An Open Label Study of the Safety, Efficacy and Pharmacokinetics of Glycerol Phenylbutyrate (GPB; RAVICTI®) in Pediatric Subjects Under Two Years of Age With Urea Cycle Disorders (UCDs)

Sponsor: Amgen

Interventions RAVICTI
Updated 10 times since 2017 Last updated: Jun 18, 2024 Started: Dec 31, 2014 Primary completion: Oct 17, 2016 Completion: Jul 17, 2017
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE4 clinical study on Urea Cycle Disorder, this trial is completed. The trial is conducted by Amgen and has accumulated 10 data snapshots since 2014. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotRecruiting~Feb 2017 – ~Sep 2017 · 7 months · monthly snapshotActive Not Recruiting~Sep 2017 – ~Jun 2018 · 9 months · monthly snapshotCompleted~Jun 2018 – ~Apr 2019 · 10 months · monthly snapshotCompleted~Apr 2019 – ~Jan 2021 · 21 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshotCompleted~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 12 months · monthly snapshotCompleted

Change History

10 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE4

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE4

  3. Aug 2024 — Sep 2024 [monthly]

    Completed PHASE4

  4. Jul 2024 — Aug 2024 [monthly]

    Completed PHASE4

  5. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE4

Show 5 earlier versions
  1. Apr 2019 — Jan 2021 [monthly]

    Completed PHASE4

  2. Jun 2018 — Apr 2019 [monthly]

    Completed PHASE4

  3. Sep 2017 — Jun 2018 [monthly]

    Completed PHASE4

    Status: Active Not RecruitingCompleted

  4. Feb 2017 — Sep 2017 [monthly]

    Active Not Recruiting PHASE4

    Status: RecruitingActive Not Recruiting

  5. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE4

    First recorded

Dec 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Amgen
Data source: Amgen

For direct contact, visit the study record on ClinicalTrials.gov .