deltatrials
Completed PHASE1/PHASE2 NCT02268253

Tagraxofusp (SL-401) in Participants With Chronic Myelomonocytic Leukemia (CMML) and Myelofibrosis (MF)

Tagraxofusp (SL-401) in Patients With Chronic Myelomonocytic Leukemia (CMML)

Sponsor: Stemline Therapeutics, Inc.

Updated 16 times since 2017 Last updated: Dec 23, 2024 Started: Feb 10, 2016 Primary completion: Mar 27, 2023 Completion: Mar 27, 2023

A PHASE1/PHASE2 clinical study on Chronic Myelomonocytic Leukemia and Myelofibrosis, this trial is completed. The trial is conducted by Stemline Therapeutics, Inc. and has accumulated 16 data snapshots since 2016. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Feb 2018 · 12 months · monthly snapshot~Feb 2018 – ~Jun 2018 · 4 months · monthly snapshot~Jun 2018 – ~Apr 2019 · 10 months · monthly snapshot~Apr 2019 – ~Jan 2020 · 9 months · monthly snapshot~Jan 2020 – ~Feb 2020 · 31 days · monthly snapshot~Feb 2020 – ~Jul 2020 · 5 months · monthly snapshot~Jul 2020 – ~Jan 2021 · 6 months · monthly snapshot~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshot~Sep 2021 – ~May 2022 · 8 months · monthly snapshot~May 2022 – ~Feb 2023 · 9 months · monthly snapshot~Feb 2023 – ~Apr 2023 · 59 days · monthly snapshot~Apr 2023 – ~Jul 2024 · 15 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Feb 2025 · 5 months · monthly snapshot~Feb 2025 – present · 14 months · monthly snapshot

Change History

16 versions recorded
  1. Feb 2025 — Present [monthly]

    Completed PHASE1/PHASE2

    Phase: PHASE2PHASE1/PHASE2

  2. Sep 2024 — Feb 2025 [monthly]

    Completed PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  4. Apr 2023 — Jul 2024 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

  5. Feb 2023 — Apr 2023 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

Show 11 earlier versions
  1. May 2022 — Feb 2023 [monthly]

    Recruiting PHASE2

  2. Sep 2021 — May 2022 [monthly]

    Recruiting PHASE2

  3. Jan 2021 — Sep 2021 [monthly]

    Recruiting PHASE2

  4. Jul 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

  5. Feb 2020 — Jul 2020 [monthly]

    Recruiting PHASE2

  6. Jan 2020 — Feb 2020 [monthly]

    Recruiting PHASE2

    Phase: PHASE1_PHASE2PHASE2

  7. Apr 2019 — Jan 2020 [monthly]

    Recruiting PHASE1_PHASE2

  8. Jun 2018 — Apr 2019 [monthly]

    Recruiting PHASE1_PHASE2

  9. Feb 2018 — Jun 2018 [monthly]

    Recruiting PHASE1_PHASE2

  10. Feb 2017 — Feb 2018 [monthly]

    Recruiting PHASE1_PHASE2

  11. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE1_PHASE2

    First recorded

Feb 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Stemline Therapeutics, Inc.
Data source: Stemline Therapeutics, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .