deltatrials
Active Not Recruiting NA INTERVENTIONAL 1-arm NCT02276547

Early Feasibility Study of the Neovasc Tiara™ Mitral Valve System (TIARA-I)

Early Feasibility Study of the Neovasc Tiara™ Mitral Transcatheter Heart Valve With the Tiara™ Transapical Delivery System

Sponsor: Shockwave Medical, Inc.

Conditions Mitral Valve Regurgitation
Interventions Mitral valve replacement
Updated 21 times since 2017 Last updated: May 12, 2025 Started: Dec 31, 2014 Primary completion: Jan 6, 2020 Completion: Aug 31, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This NA trial investigates Mitral Valve Regurgitation and is currently ongoing. Shockwave Medical, Inc. leads this study, which shows 21 recorded versions since 2014 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Nov 2017 · 9 months · monthly snapshot~Nov 2017 – ~Jun 2018 · 7 months · monthly snapshot~Jun 2018 – ~Sep 2018 · 3 months · monthly snapshot~Sep 2018 – ~Oct 2018 · 30 days · monthly snapshot~Oct 2018 – ~Mar 2019 · 5 months · monthly snapshot~Mar 2019 – ~Oct 2019 · 7 months · monthly snapshot~Oct 2019 – ~Jan 2020 · 3 months · monthly snapshot~Jan 2020 – ~Mar 2020 · 2 months · monthly snapshot~Mar 2020 – ~Oct 2020 · 7 months · monthly snapshot~Oct 2020 – ~Jan 2021 · 3 months · monthly snapshot~Jan 2021 – ~Jun 2021 · 5 months · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Feb 2022 · 5 months · monthly snapshot~Feb 2022 – ~Jun 2024 · 28 months · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Mar 2025 · 6 months · monthly snapshot~Mar 2025 – ~Jun 2025 · 3 months · monthly snapshot~Jun 2025 – ~Sep 2025 · 3 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

21 versions recorded

  1. Sep 2025 — Present [monthly]

    Active Not Recruiting NA

  2. Jun 2025 — Sep 2025 [monthly]

    Active Not Recruiting NA

  3. Mar 2025 — Jun 2025 [monthly]

    Active Not Recruiting NA

  4. Sep 2024 — Mar 2025 [monthly]

    Active Not Recruiting NA

  5. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting NA

▶ Show 16 earlier versions

  1. Jun 2024 — Jul 2024 [monthly]

    Active Not Recruiting NA

  2. Feb 2022 — Jun 2024 [monthly]

    Active Not Recruiting NA

  3. Sep 2021 — Feb 2022 [monthly]

    Active Not Recruiting NA

  4. Jun 2021 — Sep 2021 [monthly]

    Active Not Recruiting NA

  5. Jan 2021 — Jun 2021 [monthly]

    Active Not Recruiting NA

  6. Oct 2020 — Jan 2021 [monthly]

    Active Not Recruiting NA

  7. Mar 2020 — Oct 2020 [monthly]

    Active Not Recruiting NA

  8. Jan 2020 — Mar 2020 [monthly]

    Active Not Recruiting NA

    Status: Recruiting → Active Not Recruiting

  9. Oct 2019 — Jan 2020 [monthly]

    Recruiting NA

  10. Mar 2019 — Oct 2019 [monthly]

    Recruiting NA

  11. Oct 2018 — Mar 2019 [monthly]

    Recruiting NA

  12. Sep 2018 — Oct 2018 [monthly]

    Recruiting NA

  13. Jun 2018 — Sep 2018 [monthly]

    Recruiting NA

  14. Nov 2017 — Jun 2018 [monthly]

    Recruiting NA

  15. Feb 2017 — Nov 2017 [monthly]

    Recruiting NA

  16. Jan 2017 — Feb 2017 [monthly]

    Recruiting NA

    First recorded

Dec 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Shockwave Medical, Inc.
Data source: Shockwave Medical, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations