deltatrials
Completed PHASE1 INTERVENTIONAL 1-arm NCT02279433

A First-in-human Study to Evaluate the Safety, Tolerability and Pharmacokinetics of DS-6051b

A Phase 1/1B Multi-Center, Non Randomized, Open-Label, Multiple Dose First-In-Human Study Of DS-6051b, An Oral ROS1 And NTRK Inhibitor, In Subjects With Metastatic and/or Unresectable Solid Tumors

Sponsor: AnHeart Therapeutics Inc.

Conditions Solid Tumors
Interventions DS6051b
Updated 11 times since 2017 Last updated: Jun 18, 2025 Started: Sep 30, 2014 Primary completion: Mar 31, 2019 Completion: Mar 31, 2019
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Solid Tumors and is currently completed. AnHeart Therapeutics Inc. leads this study, which shows 11 recorded versions since 2014 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotRecruiting~Feb 2017 – ~Sep 2017 · 7 months · monthly snapshotRecruiting~Sep 2017 – ~Oct 2017 · 30 days · monthly snapshotRecruiting~Oct 2017 – ~Jun 2018 · 8 months · monthly snapshotActive Not Recruiting~Jun 2018 – ~May 2019 · 11 months · monthly snapshotActive Not Recruiting~May 2019 – ~Oct 2020 · 17 months · monthly snapshotActive Not Recruiting~Oct 2020 – ~Jan 2021 · 3 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Jul 2025 · 10 months · monthly snapshotCompleted~Jul 2025 – present · 12 months · monthly snapshotCompleted

Change History

11 versions recorded
  1. Jul 2025 — Present [monthly]

    Completed PHASE1

  2. Sep 2024 — Jul 2025 [monthly]

    Completed PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  4. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE1

  5. Oct 2020 — Jan 2021 [monthly]

    Completed PHASE1

    Status: Active Not RecruitingCompleted

Show 6 earlier versions
  1. May 2019 — Oct 2020 [monthly]

    Active Not Recruiting PHASE1

  2. Jun 2018 — May 2019 [monthly]

    Active Not Recruiting PHASE1

  3. Oct 2017 — Jun 2018 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  4. Sep 2017 — Oct 2017 [monthly]

    Recruiting PHASE1

  5. Feb 2017 — Sep 2017 [monthly]

    Recruiting PHASE1

  6. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE1

    First recorded

Sep 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • AnHeart Therapeutics Inc.
  • Nuvation Bio Inc.
Data source: Nuvation Bio Inc.

For direct contact, visit the study record on ClinicalTrials.gov .