deltatrials
Completed PHASE1/PHASE2 INTERVENTIONAL 1-arm NCT02282657

Strategy of UltraProtective Lung Ventilation With Extracorporeal CO2 Removal for New-Onset Moderate to seVere ARDS (SUPERNOVA)

Pilot Feasibility and Safety Study on Low-flow Extracorporeal CO2 Removal in Patients With Moderate ARDS to Enhance Lung Protective Ventilation

Sponsor: European Society of Intensive Care Medicine

Conditions Moderate Acute Respiratory Distress Syndrome
Interventions ECCO2R will be initiated during the 2-hour run-in time Level of carbon dioxide released at the end of expiration Neuromuscular blocking agents (NMBA) Respiratory Rate Respiratory rate will be adapted Sweep gas flow Ventilation Ventilation will be adapted
Updated 7 times since 2017 Last updated: Aug 3, 2017 Started: Nov 30, 2015 Primary completion: Jul 31, 2017 Completion: Jul 30, 2017
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02282657, this PHASE1/PHASE2 trial focuses on Moderate Acute Respiratory Distress Syndrome and remains completed. Sponsored by European Society of Intensive Care Medicine, it has been updated 7 times since 2015, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotRecruiting~Feb 2017 – ~Aug 2017 · 6 months · monthly snapshotRecruiting~Aug 2017 – ~Jun 2018 · 10 months · monthly snapshotCompleted~Jun 2018 – ~Jan 2021 · 31 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 22 months · monthly snapshotCompleted

Change History

7 versions recorded

  1. Sep 2024 — Present [monthly]

    Completed PHASE1/PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1/PHASE2

    Phase: PHASE1_PHASE2 → PHASE1/PHASE2

  3. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE1_PHASE2

  4. Jun 2018 — Jan 2021 [monthly]

    Completed PHASE1_PHASE2

  5. Aug 2017 — Jun 2018 [monthly]

    Completed PHASE1_PHASE2

    Status: Recruiting → Completed

▶ Show 2 earlier versions

  1. Feb 2017 — Aug 2017 [monthly]

    Recruiting PHASE1_PHASE2

  2. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE1_PHASE2

    First recorded

Nov 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • European Society of Intensive Care Medicine
Data source: European Society of Intensive Care Medicine

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations