Completed PHASE2 INTERVENTIONAL 2-arm NCT02296190

Efficacy and Safety of Intranasal MSP-2017 (Etripamil) for the Conversion of PSVT to Sinus Rhythm (NODE-1)

Multi-Center, Placebo-Controlled, Dose-Ranging Phase 2 Electrophysiological Study of Intranasal Administration of MSP-2017 for the Conversion of Induced Paroxysmal Supraventricular Tachycardia (PSVT) to Sinus Rhythm

Sponsor: Medpace, Inc.

Conditions Paroxysmal Supraventricular Tachycardia (PSVT)

Interventions Etripamil Placebo

Updated 8 times since 2017 Last updated: Dec 4, 2020 Started: Mar 27, 2015 Primary completion: Dec 31, 2016 Completion: Dec 31, 2016

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02296190, this PHASE2 trial focuses on Paroxysmal Supraventricular Tachycardia (PSVT) and remains completed. Sponsored by Medpace, Inc., it has been updated 8 times since 2015, reflecting limited change activity. This study contributes longitudinal data to the cardiovascular research landscape.

Status Flow

Change History

8 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE2
Sep 2024 — Sep 2025 [monthly]

Completed PHASE2
Jul 2024 — Sep 2024 [monthly]

Completed PHASE2
Jan 2021 — Jul 2024 [monthly]

Completed PHASE2
Apr 2019 — Jan 2021 [monthly]

Completed PHASE2

▶ Show 3 earlier versions

Jun 2018 — Apr 2019 [monthly]

Completed PHASE2
Feb 2017 — Jun 2018 [monthly]

Completed PHASE2

Status: Recruiting → Completed
Jan 2017 — Feb 2017 [monthly]

Recruiting PHASE2

First recorded

Mar 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Medpace, Inc.
Milestone Pharmaceuticals Inc.

Data source: Milestone Pharmaceuticals Inc.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Atlanta, United States , Austin, United States , Baltimore, United States , Canton, United States , Charlottesville, United States , Cincinnati, United States , Houston, United States , Jacksonville, United States , Kansas City, United States , Littleton, United States and 14 more locations