deltatrials
Terminated PHASE2 INTERVENTIONAL 2-arm NCT02303041

Pilot Study of Sonidegib and Buparlisib in Treating Patients With Advanced or Metastatic Basal Cell Carcinoma

An Open-Label Pilot Study to Evaluate the Efficacy and Safety of a Combination Treatment of Sonidegib (LDE225) and Buparlisib (BKM120) For the Treatment of Advanced Basal Cell Carcinomas

Sponsor: Anne Chang

Updated 9 times since 2017 Last updated: Jan 10, 2019 Started: Feb 28, 2015 Primary completion: Apr 30, 2017 Completion: Jun 30, 2017
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Business Decision

A PHASE2 clinical study on Basal Cell Nevus Syndrome and Carcinoma, Basal Cell, this trial is terminated or withdrawn. The trial is conducted by Anne Chang and has accumulated 9 data snapshots since 2015. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotActive Not Recruiting~Feb 2017 – ~May 2017 · 3 months · monthly snapshotActive Not Recruiting~May 2017 – ~May 2018 · 12 months · monthly snapshotActive Not Recruiting~May 2018 – ~Jun 2018 · 31 days · monthly snapshotCompleted~Jun 2018 – ~Feb 2019 · 8 months · monthly snapshotCompleted~Feb 2019 – ~Jan 2021 · 23 months · monthly snapshotTerminated~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – present · 23 months · monthly snapshotTerminated

Change History

9 versions recorded
  1. Sep 2024 — Present [monthly]

    Terminated PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE2

  3. Jan 2021 — Jul 2024 [monthly]

    Terminated PHASE2

  4. Feb 2019 — Jan 2021 [monthly]

    Terminated PHASE2

    Status: CompletedTerminated

  5. Jun 2018 — Feb 2019 [monthly]

    Completed PHASE2

Show 4 earlier versions
  1. May 2018 — Jun 2018 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted · Phase: NAPHASE2

  2. May 2017 — May 2018 [monthly]

    Active Not Recruiting NA

  3. Feb 2017 — May 2017 [monthly]

    Active Not Recruiting NA

  4. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting NA

    First recorded

Feb 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Anne Chang
  • Novartis Pharmaceuticals
Data source: Stanford University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations