deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT02316353

A Study to Evaluate the Long-term Clinical Safety and Efficacy of Subcutaneously Administered C1-esterase Inhibitor in the Prevention of Hereditary Angioedema

An Open-label, Randomized Study to Evaluate the Long-term Clinical Safety and Efficacy of Subcutaneous Administration of Human Plasma-derived C1-esterase Inhibitor in the Prophylactic Treatment of Hereditary Angioedema

Sponsor: CSL Behring

Updated 14 times since 2017 Last updated: Oct 17, 2018 Started: Dec 31, 2014 Primary completion: Sep 21, 2017 Completion: Sep 21, 2017
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02316353, this PHASE3 trial focuses on Hereditary Angioedema Types I and II and remains completed. Sponsored by CSL Behring, it has been updated 14 times since 2014, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Jun 2017 · 4 months · monthly snapshot~Jun 2017 – ~Sep 2017 · 3 months · monthly snapshot~Sep 2017 – ~Oct 2017 · 30 days · monthly snapshot~Oct 2017 – ~Nov 2017 · 31 days · monthly snapshot~Nov 2017 – ~Apr 2018 · 5 months · monthly snapshot~Apr 2018 – ~Jun 2018 · 2 months · monthly snapshot~Jun 2018 – ~Dec 2018 · 6 months · monthly snapshot~Dec 2018 – ~Jan 2021 · 25 months · monthly snapshot~Jan 2021 – ~Dec 2021 · 11 months · monthly snapshot~Dec 2021 – ~Jul 2024 · 31 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 12 months · monthly snapshot

Change History

14 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Dec 2021 — Jul 2024 [monthly]

    Completed PHASE3

  5. Jan 2021 — Dec 2021 [monthly]

    Completed PHASE3

Show 9 earlier versions
  1. Dec 2018 — Jan 2021 [monthly]

    Completed PHASE3

  2. Jun 2018 — Dec 2018 [monthly]

    Completed PHASE3

  3. Apr 2018 — Jun 2018 [monthly]

    Completed PHASE3

  4. Nov 2017 — Apr 2018 [monthly]

    Completed PHASE3

    Status: Active Not RecruitingCompleted

  5. Oct 2017 — Nov 2017 [monthly]

    Active Not Recruiting PHASE3

  6. Sep 2017 — Oct 2017 [monthly]

    Active Not Recruiting PHASE3

  7. Jun 2017 — Sep 2017 [monthly]

    Active Not Recruiting PHASE3

  8. Feb 2017 — Jun 2017 [monthly]

    Active Not Recruiting PHASE3

  9. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE3

    First recorded

Dec 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • CSL Behring
Data source: CSL Behring

For direct contact, visit the study record on ClinicalTrials.gov .