deltatrials
Completed PHASE1 INTERVENTIONAL 1-arm NCT02317016

Study to Assess the Effect of AZD9291 on the Blood Levels of Rosuvastatin, in Patients With EGFRm+ Non-small Cell Lung Cancer

A Phase I, Open-Label, Non-Randomised, Multicentre Study to Assess the Effect of AZD9291 on the Pharmacokinetics of Rosuvastatin (a Sensitive BCRP Substrate) in Patients With EGFRm Positive NSCLC Whose Disease Has Progressed on an EGFR TKI

Sponsor: AstraZeneca

Updated 12 times since 2017 Last updated: Jul 2, 2018 Started: Mar 10, 2015 Primary completion: Jul 11, 2015 Completion: May 22, 2018
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02317016, this PHASE1 trial focuses on Non Small Cell Lung Cancer and remains completed. Sponsored by AstraZeneca, it has been updated 12 times since 2015, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotActive Not Recruiting~Feb 2017 – ~Jul 2017 · 5 months · monthly snapshotActive Not Recruiting~Jul 2017 – ~Aug 2017 · 31 days · monthly snapshotActive Not Recruiting~Aug 2017 – ~Nov 2017 · 3 months · monthly snapshotActive Not Recruiting~Nov 2017 – ~Jun 2018 · 7 months · monthly snapshotActive Not Recruiting~Jun 2018 – ~Aug 2018 · 2 months · monthly snapshotActive Not Recruiting~Aug 2018 – ~Jan 2021 · 29 months · monthly snapshotCompleted~Jan 2021 – ~Dec 2021 · 11 months · monthly snapshotCompleted~Dec 2021 – ~Jul 2024 · 31 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 10 months · monthly snapshotCompleted

Change History

12 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE1

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  4. Dec 2021 — Jul 2024 [monthly]

    Completed PHASE1

  5. Jan 2021 — Dec 2021 [monthly]

    Completed PHASE1

Show 7 earlier versions
  1. Aug 2018 — Jan 2021 [monthly]

    Completed PHASE1

    Status: Active Not RecruitingCompleted

  2. Jun 2018 — Aug 2018 [monthly]

    Active Not Recruiting PHASE1

  3. Nov 2017 — Jun 2018 [monthly]

    Active Not Recruiting PHASE1

  4. Aug 2017 — Nov 2017 [monthly]

    Active Not Recruiting PHASE1

  5. Jul 2017 — Aug 2017 [monthly]

    Active Not Recruiting PHASE1

  6. Feb 2017 — Jul 2017 [monthly]

    Active Not Recruiting PHASE1

  7. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE1

    First recorded

Mar 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • AstraZeneca
Data source: AstraZeneca

For direct contact, visit the study record on ClinicalTrials.gov .