deltatrials
Terminated PHASE2/PHASE3 INTERVENTIONAL 1-arm NCT02326285

Induction Therapy With Intercalated Tyrosine Kinase Inhibitor (TKI) and Chemotherapy in NSCLC With Activating Epidermal Growth Factor Receptor (EGFR) Mutation in Stages II-IIIB (NeoIntercal)

Induction Therapy With Gefitinib Followed by Taxane Platinum Chemotherapy and Intercalated Gefitinib in NSCLC Stages II-IIIB With Activating EGFR Mutation - A Single Arm Phase II Trial.

Sponsor: AIO-Studien-gGmbH

Updated 10 times since 2017 Last updated: Jan 19, 2018 Started: Nov 30, 2015 Primary completion: Mar 28, 2017 Completion: Jan 31, 2018
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Due to low patient enrollment was stopped. Only one patient could be enrolled. 37 patients were pre-screened, but not into the inclusion criteria (wt-EGFR)

A PHASE2/PHASE3 clinical study on Activating EGFR Mutation and NSCLC, this trial is terminated or withdrawn. The trial is conducted by AIO-Studien-gGmbH and has accumulated 10 data snapshots since 2015. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Sep 2017 · 8 months · monthly snapshotRecruiting~Sep 2017 – ~Feb 2018 · 5 months · monthly snapshotTerminated~Feb 2018 – ~May 2018 · 3 months · monthly snapshotTerminated~May 2018 – ~Jun 2018 · 31 days · monthly snapshotTerminated~Jun 2018 – ~Nov 2020 · 29 months · monthly snapshotTerminated~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshotTerminated~Jan 2021 – ~Dec 2021 · 11 months · monthly snapshotTerminated~Dec 2021 – ~Jul 2024 · 31 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – present · 22 months · monthly snapshotTerminated

Change History

10 versions recorded
  1. Sep 2024 — Present [monthly]

    Terminated PHASE2/PHASE3

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE2/PHASE3

    Phase: PHASE2_PHASE3PHASE2/PHASE3

  3. Dec 2021 — Jul 2024 [monthly]

    Terminated PHASE2_PHASE3

  4. Jan 2021 — Dec 2021 [monthly]

    Terminated PHASE2_PHASE3

  5. Nov 2020 — Jan 2021 [monthly]

    Terminated PHASE2_PHASE3

Show 5 earlier versions
  1. Jun 2018 — Nov 2020 [monthly]

    Terminated PHASE2_PHASE3

  2. May 2018 — Jun 2018 [monthly]

    Terminated PHASE2_PHASE3

  3. Feb 2018 — May 2018 [monthly]

    Terminated PHASE2_PHASE3

  4. Sep 2017 — Feb 2018 [monthly]

    Terminated PHASE2_PHASE3

    Status: RecruitingTerminated

  5. Jan 2017 — Sep 2017 [monthly]

    Recruiting PHASE2_PHASE3

    First recorded

Nov 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • AIO-Studien-gGmbH
  • AstraZeneca
Data source: AIO-Studien-gGmbH

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations