deltatrials
Completed PHASE2 INTERVENTIONAL 3-arm NCT02335411

A Study of Pembrolizumab (MK-3475) in Participants With Recurrent or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma (MK-3475-059/KEYNOTE-059)

A Phase II Clinical Trial of Pembrolizumab as Monotherapy and in Combination With Cisplatin+5-Fluorouracil in Subjects With Recurrent or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma (KEYNOTE-059)

Sponsor: Merck Sharp & Dohme LLC

Updated 15 times since 2017 Last updated: Jul 13, 2022 Started: Feb 3, 2015 Primary completion: Jul 23, 2021 Completion: Jul 23, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Gastric Adenocarcinoma and Gastroesophageal Junction Adenocarcinoma, this trial is completed. The trial is conducted by Merck Sharp & Dohme LLC and has accumulated 15 data snapshots since 2015. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Dec 2017 · 10 months · monthly snapshot~Dec 2017 – ~Jun 2018 · 6 months · monthly snapshot~Jun 2018 – ~May 2019 · 11 months · monthly snapshot~May 2019 – ~Jul 2019 · 2 months · monthly snapshot~Jul 2019 – ~Feb 2020 · 7 months · monthly snapshot~Feb 2020 – ~Mar 2020 · 29 days · monthly snapshot~Mar 2020 – ~Jun 2020 · 3 months · monthly snapshot~Jun 2020 – ~Jan 2021 · 7 months · monthly snapshot~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshot~Sep 2021 – ~Jun 2022 · 9 months · monthly snapshot~Jun 2022 – ~Sep 2022 · 3 months · monthly snapshot~Sep 2022 – ~Jul 2024 · 22 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 22 months · monthly snapshot

Change History

15 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  3. Sep 2022 — Jul 2024 [monthly]

    Completed PHASE2

  4. Jun 2022 — Sep 2022 [monthly]

    Completed PHASE2

  5. Sep 2021 — Jun 2022 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

Show 10 earlier versions
  1. Jan 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE2

  2. Jun 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE2

  3. Mar 2020 — Jun 2020 [monthly]

    Active Not Recruiting PHASE2

  4. Feb 2020 — Mar 2020 [monthly]

    Active Not Recruiting PHASE2

  5. Jul 2019 — Feb 2020 [monthly]

    Active Not Recruiting PHASE2

  6. May 2019 — Jul 2019 [monthly]

    Active Not Recruiting PHASE2

  7. Jun 2018 — May 2019 [monthly]

    Active Not Recruiting PHASE2

  8. Dec 2017 — Jun 2018 [monthly]

    Active Not Recruiting PHASE2

  9. Feb 2017 — Dec 2017 [monthly]

    Active Not Recruiting PHASE2

  10. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE2

    First recorded

Feb 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Merck Sharp & Dohme LLC
Data source: Merck Sharp & Dohme LLC

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

No location information available.