deltatrials
Unknown NA INTERVENTIONAL 2-arm NCT02386670

Prevention of Alzheimer's Disease With CR Plus tDCS in Mild Cognitive Impairment and Depression (PACt-MD) (PACt-MD)

Prevention of Alzheimer's Dimentia With Cognitive Remediation Plus Transcranial Direct Current Stimulation in Mild Cognitive Impairment and Depression

Sponsor: Applied Health Research Centre

Conditions Major Depressive Disorder, Recurrent, In Remission Major Depressive Disorder, Single Episode, in Full Remission Mild Cognitive Impairment
Interventions sham tDCS + sham CR tDCS + CR
Updated 13 times since 2017 Last updated: Feb 23, 2024 Started: Jan 31, 2015 Primary completion: Dec 31, 2022 Completion: Dec 31, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02386670, this NA trial focuses on Major Depressive Disorder, Recurrent, In Remission and Major Depressive Disorder, Single Episode, in Full Remission and remains ongoing. Sponsored by Applied Health Research Centre, it has been updated 13 times since 2015, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Jun 2018 · 17 months · monthly snapshot~Jun 2018 – ~Jan 2020 · 19 months · monthly snapshot~Jan 2020 – ~Aug 2020 · 7 months · monthly snapshot~Aug 2020 – ~Jan 2021 · 5 months · monthly snapshot~Jan 2021 – ~May 2021 · 4 months · monthly snapshot~May 2021 – ~May 2023 · 24 months · monthly snapshot~May 2023 – ~Mar 2024 · 10 months · monthly snapshot~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Apr 2025 · 7 months · monthly snapshot~Apr 2025 – ~Jun 2025 · 2 months · monthly snapshot~Jun 2025 – ~Mar 2026 · 9 months · monthly snapshot~Mar 2026 – present · 4 months · monthly snapshot

Change History

13 versions recorded

  1. Mar 2026 — Present [monthly]

    Unknown NA

    Status: Active Not Recruiting → Unknown

  2. Jun 2025 — Mar 2026 [monthly]

    Active Not Recruiting NA

  3. Apr 2025 — Jun 2025 [monthly]

    Active Not Recruiting NA

  4. Sep 2024 — Apr 2025 [monthly]

    Active Not Recruiting NA

  5. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting NA

▶ Show 8 earlier versions

  1. Mar 2024 — Jul 2024 [monthly]

    Active Not Recruiting NA

    Status: Unknown Status → Active Not Recruiting

  2. May 2023 — Mar 2024 [monthly]

    Unknown Status NA

    Status: Active Not Recruiting → Unknown Status

  3. May 2021 — May 2023 [monthly]

    Active Not Recruiting NA

  4. Jan 2021 — May 2021 [monthly]

    Active Not Recruiting NA

  5. Aug 2020 — Jan 2021 [monthly]

    Active Not Recruiting NA

  6. Jan 2020 — Aug 2020 [monthly]

    Active Not Recruiting NA

    Status: Recruiting → Active Not Recruiting

  7. Jun 2018 — Jan 2020 [monthly]

    Recruiting NA

  8. Jan 2017 — Jun 2018 [monthly]

    Recruiting NA

    First recorded

Jan 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Applied Health Research Centre
  • Baycrest Centre for Geriatric Care
  • Brain Canada
  • Centre for Addiction and Mental Health
  • Queen's University
  • Sunnybrook Health Sciences Centre
  • Unity Health Toronto
  • University Health Network, Toronto
Data source: Centre for Addiction and Mental Health

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations