deltatrials
Completed PHASE1 INTERVENTIONAL 2-arm NCT02389842

PIPA: Combination of PI3 Kinase Inhibitors and PAlbociclib (PIPA)

PIPA: a Phase Ib Study to Assess the Safety, Tolerability and Efficacy of the PI3K Inhibitors, Taselisib (GDC-0032) or Pictilisib (GDC-0941), in Combination with PAlbociclib, with the Subsequent Addition of Fulvestrant in PIK3CA-mutant Breast Cancers

Sponsor: Institute of Cancer Research, United Kingdom

Updated 9 times since 2017 Last updated: Sep 24, 2024 Started: Mar 25, 2015 Primary completion: Oct 31, 2018 Completion: May 26, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Advanced Solid Tumours and Breast Cancer and is currently completed. Institute of Cancer Research, United Kingdom leads this study, which shows 9 recorded versions since 2015 — indicating limited longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jan 2017 – ~Sep 2017 · 8 months · monthly snapshotRecruiting~Sep 2017 – ~Jun 2018 · 9 months · monthly snapshotUnknown Status~Jun 2018 – ~Dec 2019 · 18 months · monthly snapshotUnknown Status~Dec 2019 – ~Jan 2021 · 13 months · monthly snapshotActive Not Recruiting~Jan 2021 – ~Mar 2022 · 14 months · monthly snapshotActive Not Recruiting~Mar 2022 – ~Jul 2024 · 28 months · monthly snapshotUnknown Status~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotUnknown~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshotUnknown~Oct 2024 – present · 20 months · monthly snapshotCompleted

Change History

9 versions recorded
  1. Oct 2024 — Present [monthly]

    Completed PHASE1

    Status: UnknownCompleted

  2. Sep 2024 — Oct 2024 [monthly]

    Unknown PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Unknown PHASE1

    Status: Unknown StatusUnknown

  4. Mar 2022 — Jul 2024 [monthly]

    Unknown Status PHASE1

    Status: Active Not RecruitingUnknown Status

  5. Jan 2021 — Mar 2022 [monthly]

    Active Not Recruiting PHASE1

Show 4 earlier versions
  1. Dec 2019 — Jan 2021 [monthly]

    Active Not Recruiting PHASE1

    Status: Unknown StatusActive Not Recruiting

  2. Jun 2018 — Dec 2019 [monthly]

    Unknown Status PHASE1

  3. Sep 2017 — Jun 2018 [monthly]

    Unknown Status PHASE1

    Status: RecruitingUnknown Status

  4. Jan 2017 — Sep 2017 [monthly]

    Recruiting PHASE1

    First recorded

Mar 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Institute of Cancer Research, United Kingdom
  • Pfizer
  • Roche Pharma AG
  • Royal Marsden NHS Foundation Trust
Data source: Royal Marsden NHS Foundation Trust

For direct contact, visit the study record on ClinicalTrials.gov .