deltatrials
Completed PHASE2 INTERVENTIONAL 2-arm NCT02396134

Vaccine Therapy in Reducing the Frequency of Cytomegalovirus Events in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplant

A Phase II Randomized, Placebo-Controlled, Multicenter Trial to Evaluate Protective Function of an Optimized Dose of CMVPepVax in Recipients of an Allogeneic Hematopoietic Stem Cell Transplant

Sponsor: City of Hope Medical Center

Conditions Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive Adult Acute Lymphoblastic Leukemia in Remission Adult Acute Myeloid Leukemia in Remission Adult Hodgkin Lymphoma Adult Lymphoblastic Lymphoma Adult Non-Hodgkin Lymphoma Chronic Lymphocytic Leukemia Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive Cytomegaloviral Infection HLA-A*0201 Positive Cells Present Hematopoietic and Lymphoid Cell Neoplasm Myelodysplastic Syndrome Myelofibrosis Myeloproliferative Neoplasm
Interventions CMVpp65-A*0201 peptide vaccine Laboratory Biomarker Analysis Placebo
Updated 22 times since 2017 Last updated: Feb 17, 2025 Started: May 21, 2015 Primary completion: Mar 4, 2018 Completion: Sep 19, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive and Adult Acute Lymphoblastic Leukemia in Remission, this trial is completed. The trial is conducted by City of Hope Medical Center and has accumulated 22 data snapshots since 2015. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Jun 2017 · 4 months · monthly snapshot~Jun 2017 – ~Dec 2017 · 6 months · monthly snapshot~Dec 2017 – ~Jan 2018 · 31 days · monthly snapshot~Jan 2018 – ~Jun 2018 · 5 months · monthly snapshot~Jun 2018 – ~Jan 2019 · 7 months · monthly snapshot~Jan 2019 – ~Jun 2019 · 5 months · monthly snapshot~Jun 2019 – ~Aug 2019 · 2 months · monthly snapshot~Aug 2019 – ~Jan 2021 · 17 months · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Mar 2022 · 13 months · monthly snapshot~Mar 2022 – ~Feb 2023 · 11 months · monthly snapshot~Feb 2023 – ~Apr 2023 · 59 days · monthly snapshot~Apr 2023 – ~Jun 2023 · 2 months · monthly snapshot~Jun 2023 – ~Aug 2023 · 2 months · monthly snapshot~Aug 2023 – ~Sep 2023 · 31 days · monthly snapshot~Sep 2023 – ~Mar 2024 · 6 months · monthly snapshot~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Apr 2025 · 7 months · monthly snapshot~Apr 2025 – present · 12 months · monthly snapshot~Jan 2026 – present · 3 months · monthly snapshot

Change History

22 versions recorded

  1. Jan 2026 — Present [monthly]

    Completed PHASE2

  2. Apr 2025 — Present [monthly]

    Completed PHASE2

    Status: Active Not Recruiting → Completed

  3. Sep 2024 — Apr 2025 [monthly]

    Active Not Recruiting PHASE2

  4. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE2

  5. Mar 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE2

▶ Show 17 earlier versions

  1. Sep 2023 — Mar 2024 [monthly]

    Active Not Recruiting PHASE2

  2. Aug 2023 — Sep 2023 [monthly]

    Active Not Recruiting PHASE2

  3. Jun 2023 — Aug 2023 [monthly]

    Active Not Recruiting PHASE2

  4. Apr 2023 — Jun 2023 [monthly]

    Active Not Recruiting PHASE2

  5. Feb 2023 — Apr 2023 [monthly]

    Active Not Recruiting PHASE2

  6. Mar 2022 — Feb 2023 [monthly]

    Active Not Recruiting PHASE2

  7. Feb 2021 — Mar 2022 [monthly]

    Active Not Recruiting PHASE2

    Status: Recruiting → Active Not Recruiting

  8. Jan 2021 — Feb 2021 [monthly]

    Recruiting PHASE2

  9. Aug 2019 — Jan 2021 [monthly]

    Recruiting PHASE2

  10. Jun 2019 — Aug 2019 [monthly]

    Recruiting PHASE2

    Status: Active Not Recruiting → Recruiting

  11. Jan 2019 — Jun 2019 [monthly]

    Active Not Recruiting PHASE2

  12. Jun 2018 — Jan 2019 [monthly]

    Active Not Recruiting PHASE2

  13. Jan 2018 — Jun 2018 [monthly]

    Active Not Recruiting PHASE2

    Status: Recruiting → Active Not Recruiting

  14. Dec 2017 — Jan 2018 [monthly]

    Recruiting PHASE2

  15. Jun 2017 — Dec 2017 [monthly]

    Recruiting PHASE2

  16. Feb 2017 — Jun 2017 [monthly]

    Recruiting PHASE2

  17. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE2

    First recorded

May 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • City of Hope Medical Center
  • National Cancer Institute (NCI)
Data source: City of Hope Medical Center

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations