deltatrials
Completed PHASE2 INTERVENTIONAL 1-arm NCT02399215

Nintedanib in Treating Patients With Locally Advanced or Metastatic Neuroendocrine Tumors

Multicenter Phase 2 Study of Nintedanib for Patients With Advanced Carcinoid Tumors

Sponsor: National Comprehensive Cancer Network

Conditions Carcinoid Tumor Metastatic Carcinoid Tumor Neuroendocrine Neoplasm
Interventions Laboratory Biomarker Analysis Nintedanib Pharmacological Study Quality-of-Life Assessment
Updated 25 times since 2017 Last updated: Dec 6, 2023 Started: May 15, 2015 Primary completion: Sep 1, 2019 Completion: Aug 31, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Carcinoid Tumor and Metastatic Carcinoid Tumor, this trial is completed. The trial is conducted by National Comprehensive Cancer Network and has accumulated 25 data snapshots since 2015. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Dec 2017 · 10 months · monthly snapshot~Dec 2017 – ~Jun 2018 · 6 months · monthly snapshot~Jun 2018 – ~Sep 2018 · 3 months · monthly snapshot~Sep 2018 – ~Oct 2018 · 30 days · monthly snapshot~Oct 2018 – ~Feb 2019 · 4 months · monthly snapshot~Feb 2019 – ~Apr 2019 · 59 days · monthly snapshot~Apr 2019 – ~May 2019 · 30 days · monthly snapshot~May 2019 – ~Aug 2019 · 3 months · monthly snapshot~Aug 2019 – ~Oct 2019 · 2 months · monthly snapshot~Oct 2019 – ~Jan 2020 · 3 months · monthly snapshot~Jan 2020 – ~May 2020 · 4 months · monthly snapshot~May 2020 – ~Sep 2020 · 4 months · monthly snapshot~Sep 2020 – ~Nov 2020 · 2 months · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~Jun 2021 · 3 months · monthly snapshot~Jun 2021 – ~Jul 2022 · 13 months · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Jan 2023 · 4 months · monthly snapshot~Jan 2023 – ~Apr 2023 · 3 months · monthly snapshot~Apr 2023 – ~Jan 2024 · 9 months · monthly snapshot~Jan 2024 – ~Jul 2024 · 6 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 22 months · monthly snapshot

Change History

25 versions recorded

  1. Sep 2024 — Present [monthly]

    Completed PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  3. Jan 2024 — Jul 2024 [monthly]

    Completed PHASE2

  4. Apr 2023 — Jan 2024 [monthly]

    Completed PHASE2

    Status: Active Not Recruiting → Completed

  5. Jan 2023 — Apr 2023 [monthly]

    Active Not Recruiting PHASE2

▶ Show 20 earlier versions

  1. Sep 2022 — Jan 2023 [monthly]

    Active Not Recruiting PHASE2

  2. Jul 2022 — Sep 2022 [monthly]

    Active Not Recruiting PHASE2

  3. Jun 2021 — Jul 2022 [monthly]

    Active Not Recruiting PHASE2

  4. Mar 2021 — Jun 2021 [monthly]

    Active Not Recruiting PHASE2

  5. Jan 2021 — Mar 2021 [monthly]

    Active Not Recruiting PHASE2

  6. Nov 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE2

  7. Sep 2020 — Nov 2020 [monthly]

    Active Not Recruiting PHASE2

  8. May 2020 — Sep 2020 [monthly]

    Active Not Recruiting PHASE2

  9. Jan 2020 — May 2020 [monthly]

    Active Not Recruiting PHASE2

  10. Oct 2019 — Jan 2020 [monthly]

    Active Not Recruiting PHASE2

  11. Aug 2019 — Oct 2019 [monthly]

    Active Not Recruiting PHASE2

  12. May 2019 — Aug 2019 [monthly]

    Active Not Recruiting PHASE2

  13. Apr 2019 — May 2019 [monthly]

    Active Not Recruiting PHASE2

  14. Feb 2019 — Apr 2019 [monthly]

    Active Not Recruiting PHASE2

  15. Oct 2018 — Feb 2019 [monthly]

    Active Not Recruiting PHASE2

  16. Sep 2018 — Oct 2018 [monthly]

    Active Not Recruiting PHASE2

  17. Jun 2018 — Sep 2018 [monthly]

    Active Not Recruiting PHASE2

  18. Dec 2017 — Jun 2018 [monthly]

    Active Not Recruiting PHASE2

    Status: Recruiting → Active Not Recruiting

  19. Feb 2017 — Dec 2017 [monthly]

    Recruiting PHASE2

  20. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE2

    First recorded

May 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Comprehensive Cancer Network
  • Roswell Park Cancer Institute
Data source: Roswell Park Cancer Institute

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations