Completed PHASE4 INTERVENTIONAL 3-arm NCT02399397

Influence of Age, Sepsis and SLCO1A2 Polymorphisms on Rocuronium Pharmacokinetics (ROCSEPSIS)

Influence of Sepsis, Age and SLCO1A2 Genetic Polymorphisms on Rocuronium Pharmacokinetics-pharmacodynamics in ASA I-III Surgical Patients

Sponsor: Universidade Estadual Paulista Júlio de Mesquita Filho

Conditions Sepsis Septic Shock Systemic Inflammatory Response Syndrome

Interventions Blood testing for liver and renal function General anesthesia Serial blood sampling Small to medium sized surgery under general anesthesia Train of four monitoring

Updated 6 times since 2017 Last updated: Jan 24, 2017 Started: Feb 28, 2014 Primary completion: Dec 31, 2015 Completion: Dec 31, 2015

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE4 trial investigates Sepsis and Septic Shock and is currently completed. Universidade Estadual Paulista Júlio de Mesquita Filho leads this study, which shows 6 recorded versions since 2014 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

Change History

6 versions recorded

Sep 2024 — Present [monthly]

Completed PHASE4
Jul 2024 — Sep 2024 [monthly]

Completed PHASE4
Jan 2021 — Jul 2024 [monthly]

Completed PHASE4
Jun 2018 — Jan 2021 [monthly]

Completed PHASE4
Feb 2017 — Jun 2018 [monthly]

Completed PHASE4

▶ Show 1 earlier version

Jan 2017 — Feb 2017 [monthly]

Completed PHASE4

First recorded

Feb 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Universidade Estadual Paulista Júlio de Mesquita Filho
University of Sao Paulo

Data source: Universidade Estadual Paulista Júlio de Mesquita Filho

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Araraquara, Brazil