deltatrials
Completed PHASE2 INTERVENTIONAL 1-arm NCT02409316

[18F]FES PET/CT in Endocrine Refractory Breast Cancer

[18F]Fluoroestradiol (FES) PET/CT Imaging to Evaluate in Vivo ER in Endocrine Refractory Metastatic Breast Cancer

Sponsor: University of Pennsylvania

Interventions [18F]FES
Updated 16 times since 2017 Last updated: Aug 7, 2025 Started: May 31, 2015 Primary completion: Aug 1, 2025 Completion: Aug 1, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Breast Neoplasm and Estrogen Receptor Positive Breast Cancer, this trial is completed. The trial is conducted by University of Pennsylvania and has accumulated 16 data snapshots since 2015. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshot~Jun 2018 – ~Dec 2018 · 6 months · monthly snapshot~Dec 2018 – ~Dec 2019 · 12 months · monthly snapshot~Dec 2019 – ~May 2020 · 5 months · monthly snapshot~May 2020 – ~Jul 2020 · 2 months · monthly snapshot~Jul 2020 – ~Oct 2020 · 3 months · monthly snapshot~Oct 2020 – ~Jan 2021 · 3 months · monthly snapshot~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshot~Sep 2021 – ~Sep 2022 · 12 months · monthly snapshot~Sep 2022 – ~Aug 2023 · 11 months · monthly snapshot~Aug 2023 – ~Jul 2024 · 11 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Feb 2025 · 5 months · monthly snapshot~Feb 2025 – ~Sep 2025 · 7 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

16 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

  2. Feb 2025 — Sep 2025 [monthly]

    Active Not Recruiting PHASE2

  3. Sep 2024 — Feb 2025 [monthly]

    Active Not Recruiting PHASE2

  4. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE2

  5. Aug 2023 — Jul 2024 [monthly]

    Active Not Recruiting PHASE2

Show 11 earlier versions
  1. Sep 2022 — Aug 2023 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  2. Sep 2021 — Sep 2022 [monthly]

    Recruiting PHASE2

  3. Jan 2021 — Sep 2021 [monthly]

    Recruiting PHASE2

  4. Oct 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

  5. Jul 2020 — Oct 2020 [monthly]

    Recruiting PHASE2

    Status: Active Not RecruitingRecruiting

  6. May 2020 — Jul 2020 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  7. Dec 2019 — May 2020 [monthly]

    Recruiting PHASE2

  8. Dec 2018 — Dec 2019 [monthly]

    Recruiting PHASE2

  9. Jun 2018 — Dec 2018 [monthly]

    Recruiting PHASE2

  10. Feb 2017 — Jun 2018 [monthly]

    Recruiting PHASE2

  11. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE2

    First recorded

May 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • University of Pennsylvania
Data source: University of Pennsylvania

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations