Completed PHASE2 INTERVENTIONAL 4-arm NCT02435862

A Clinical Trial Designed to Evaluate the Safety and Efficacy Study of Luminate® in Inducing PVD (Posterior Vitreous Detachment) in Non-Proliferative Diabetic Retinopathy

Protocol PVD-202: A Phase 2, Randomized, Double-Masked, Placebo-Controlled Multicenter Clinical Trial Designed to Evaluate the Safety and Efficacy Study of Luminate® in Inducing PVD in Non-Proliferative Diabetic Retinopathy

Sponsor: Allegro Ophthalmics, LLC

Conditions Non-Proliferative Diabetic Retinopathy

Interventions 1.0mg Luminate® 2.0mg Luminate® 3.0mg Luminate® Balanced Salt Solution for intravitreal injection in 0.10cc

Updated 8 times since 2017 Last updated: Dec 13, 2017 Started: Feb 1, 2015 Primary completion: Aug 10, 2017 Completion: Aug 10, 2017

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Non-Proliferative Diabetic Retinopathy and is currently completed. Allegro Ophthalmics, LLC leads this study, which shows 8 recorded versions since 2015 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

Change History

8 versions recorded

Sep 2024 — Present [monthly]

Completed PHASE2
Jul 2024 — Sep 2024 [monthly]

Completed PHASE2
Jan 2021 — Jul 2024 [monthly]

Completed PHASE2
Jun 2018 — Jan 2021 [monthly]

Completed PHASE2
Dec 2017 — Jun 2018 [monthly]

Completed PHASE2

Status: Unknown Status → Completed

▶ Show 3 earlier versions

May 2017 — Dec 2017 [monthly]

Unknown Status PHASE2

Status: Recruiting → Unknown Status
Feb 2017 — May 2017 [monthly]

Recruiting PHASE2
Jan 2017 — Feb 2017 [monthly]

Recruiting PHASE2

First recorded

Feb 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Allegro Ophthalmics, LLC
Duke University
Trial Runners, LLC

Data source: Allegro Ophthalmics, LLC

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Abilene, United States , Austin, United States , Fairfax, United States , Indianapolis, United States , Lakeland, United States , McAllen, United States , Mountain View, United States , New London, United States , Orange, United States , San Antonio, United States and 2 more locations