deltatrials
Completed PHASE1/PHASE2 INTERVENTIONAL 1-arm NCT02453191

TVEC and Preop Radiation for Sarcoma (4 ml Dose)

Neoadjuvant Intralesional Injection of Talimogene Laherparepvec With Concurrent Preoperative Radiation in Patients With Locally Advanced Soft Tissue Sarcomas

Sponsor: Amgen

Updated 14 times since 2017 Last updated: Jun 17, 2024 Started: Jul 13, 2015 Primary completion: Jan 22, 2019 Completion: Mar 10, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1/PHASE2 clinical study on Soft Tissue Sarcoma, this trial is completed. The trial is conducted by Amgen and has accumulated 14 data snapshots since 2015. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Jun 2017 · 4 months · monthly snapshot~Jun 2017 – ~Apr 2018 · 10 months · monthly snapshot~Apr 2018 – ~Jun 2018 · 2 months · monthly snapshot~Jun 2018 – ~Apr 2019 · 10 months · monthly snapshot~Apr 2019 – ~Jul 2020 · 15 months · monthly snapshot~Jul 2020 – ~Dec 2020 · 5 months · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Jun 2021 · 5 months · monthly snapshot~Jun 2021 – ~Jun 2022 · 12 months · monthly snapshot~Jun 2022 – ~Jul 2023 · 13 months · monthly snapshot~Jul 2023 – ~Jul 2024 · 12 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 22 months · monthly snapshot

Change History

14 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE1/PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

  3. Jul 2023 — Jul 2024 [monthly]

    Completed PHASE1_PHASE2

    Status: Active Not RecruitingCompleted

  4. Jun 2022 — Jul 2023 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  5. Jun 2021 — Jun 2022 [monthly]

    Active Not Recruiting PHASE1_PHASE2

Show 9 earlier versions
  1. Jan 2021 — Jun 2021 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  2. Dec 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  3. Jul 2020 — Dec 2020 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  4. Apr 2019 — Jul 2020 [monthly]

    Active Not Recruiting PHASE1_PHASE2

    Status: RecruitingActive Not Recruiting

  5. Jun 2018 — Apr 2019 [monthly]

    Recruiting PHASE1_PHASE2

  6. Apr 2018 — Jun 2018 [monthly]

    Recruiting PHASE1_PHASE2

  7. Jun 2017 — Apr 2018 [monthly]

    Recruiting PHASE1_PHASE2

  8. Feb 2017 — Jun 2017 [monthly]

    Recruiting PHASE1_PHASE2

  9. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE1_PHASE2

    First recorded

Jul 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Amgen
  • University of Iowa
Data source: University of Iowa

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations