deltatrials
Completed PHASE4 INTERVENTIONAL 1-arm NCT02455622

Long-term Evaluation on Height and Weight in Patients With MPS II Who Started Treatment at < 6 Years of Age

A Long-Term, Open-Label, Multicenter, Phase IV Study to Assess Longitudinal Changes on Height and Weight in Patients With MPS II Who Are Receiving Elaprase and Started Treatment With Elaprase at <6 Years of Age

Sponsor: Shire

Updated 13 times since 2017 Last updated: Aug 5, 2025 Started: Oct 28, 2015 Primary completion: Jul 29, 2025 Completion: Jul 29, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02455622, this PHASE4 trial focuses on Hunter Syndrome and remains completed. Sponsored by Shire, it has been updated 13 times since 2015, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshot~Jun 2018 – ~Jun 2019 · 12 months · monthly snapshot~Jun 2019 – ~Mar 2020 · 9 months · monthly snapshot~Mar 2020 – ~Jan 2021 · 10 months · monthly snapshot~Jan 2021 – ~Apr 2021 · 3 months · monthly snapshot~Apr 2021 – ~Jun 2022 · 14 months · monthly snapshot~Jun 2022 – ~Aug 2023 · 14 months · monthly snapshot~Aug 2023 – ~Jul 2024 · 11 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Jan 2025 · 4 months · monthly snapshot~Jan 2025 – ~Sep 2025 · 8 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

13 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE4

    Status: Active Not RecruitingCompleted

  2. Jan 2025 — Sep 2025 [monthly]

    Active Not Recruiting PHASE4

  3. Sep 2024 — Jan 2025 [monthly]

    Active Not Recruiting PHASE4

  4. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE4

  5. Aug 2023 — Jul 2024 [monthly]

    Active Not Recruiting PHASE4

Show 8 earlier versions
  1. Jun 2022 — Aug 2023 [monthly]

    Active Not Recruiting PHASE4

  2. Apr 2021 — Jun 2022 [monthly]

    Active Not Recruiting PHASE4

  3. Jan 2021 — Apr 2021 [monthly]

    Active Not Recruiting PHASE4

  4. Mar 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE4

  5. Jun 2019 — Mar 2020 [monthly]

    Active Not Recruiting PHASE4

  6. Jun 2018 — Jun 2019 [monthly]

    Active Not Recruiting PHASE4

    Status: RecruitingActive Not Recruiting

  7. Feb 2017 — Jun 2018 [monthly]

    Recruiting PHASE4

  8. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE4

    First recorded

Oct 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Shire
  • Takeda Development Center Americas, Inc.
Data source: Takeda

For direct contact, visit the study record on ClinicalTrials.gov .