deltatrials
Completed PHASE1 INTERVENTIONAL 1-arm NCT02457845

HSV G207 Alone or With a Single Radiation Dose in Children With Progressive or Recurrent Supratentorial Brain Tumors

Phase I Clinical Trial of HSV G207 Alone or With a Single Radiation Dose in Children With Recurrent Supratentorial Brain Tumors

Sponsor: Battle for a Cure Foundation

Conditions Anaplastic Astrocytoma Cerebral Primitive Neuroectodermal Tumor Embryonal Tumor Glioblastoma Malignant Glioma PNET Supratentorial Neoplasms, Malignant
Interventions G207
Updated 26 times since 2017 Last updated: Jan 18, 2024 Started: May 31, 2016 Primary completion: Jun 30, 2020 Completion: Jan 31, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02457845, this PHASE1 trial focuses on Anaplastic Astrocytoma and Cerebral Primitive Neuroectodermal Tumor and remains completed. Sponsored by Battle for a Cure Foundation, it has been updated 26 times since 2016, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Jan 2018 · 11 months · monthly snapshot~Jan 2018 – ~Feb 2018 · 31 days · monthly snapshot~Feb 2018 – ~Jun 2018 · 4 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshot~Aug 2018 – ~Dec 2018 · 4 months · monthly snapshot~Dec 2018 – ~Jun 2019 · 6 months · monthly snapshot~Jun 2019 – ~Oct 2019 · 4 months · monthly snapshot~Oct 2019 – ~Mar 2020 · 5 months · monthly snapshot~Mar 2020 – ~Jul 2020 · 4 months · monthly snapshot~Jul 2020 – ~Sep 2020 · 2 months · monthly snapshot~Sep 2020 – ~Jan 2021 · 4 months · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Sep 2021 · 7 months · monthly snapshot~Sep 2021 – ~Feb 2022 · 5 months · monthly snapshot~Feb 2022 – ~Jul 2022 · 5 months · monthly snapshot~Jul 2022 – ~Dec 2022 · 5 months · monthly snapshot~Dec 2022 – ~Mar 2023 · 3 months · monthly snapshot~Mar 2023 – ~Apr 2023 · 31 days · monthly snapshot~Apr 2023 – ~Feb 2024 · 10 months · monthly snapshot~Feb 2024 – ~Jul 2024 · 5 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Feb 2025 · 5 months · monthly snapshot~Feb 2025 – ~Jun 2025 · 4 months · monthly snapshot~Jun 2025 – present · 14 months · monthly snapshot

Change History

26 versions recorded

  1. Jun 2025 — Present [monthly]

    Completed PHASE1

  2. Feb 2025 — Jun 2025 [monthly]

    Completed PHASE1

  3. Sep 2024 — Feb 2025 [monthly]

    Completed PHASE1

  4. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  5. Feb 2024 — Jul 2024 [monthly]

    Completed PHASE1

    Status: Active Not Recruiting → Completed

▶ Show 21 earlier versions

  1. Apr 2023 — Feb 2024 [monthly]

    Active Not Recruiting PHASE1

  2. Mar 2023 — Apr 2023 [monthly]

    Active Not Recruiting PHASE1

  3. Dec 2022 — Mar 2023 [monthly]

    Active Not Recruiting PHASE1

  4. Jul 2022 — Dec 2022 [monthly]

    Active Not Recruiting PHASE1

  5. Feb 2022 — Jul 2022 [monthly]

    Active Not Recruiting PHASE1

  6. Sep 2021 — Feb 2022 [monthly]

    Active Not Recruiting PHASE1

  7. Feb 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE1

  8. Jan 2021 — Feb 2021 [monthly]

    Active Not Recruiting PHASE1

  9. Sep 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE1

    Status: Recruiting → Active Not Recruiting

  10. Jul 2020 — Sep 2020 [monthly]

    Recruiting PHASE1

  11. Mar 2020 — Jul 2020 [monthly]

    Recruiting PHASE1

  12. Oct 2019 — Mar 2020 [monthly]

    Recruiting PHASE1

  13. Jun 2019 — Oct 2019 [monthly]

    Recruiting PHASE1

  14. Dec 2018 — Jun 2019 [monthly]

    Recruiting PHASE1

  15. Aug 2018 — Dec 2018 [monthly]

    Recruiting PHASE1

  16. Jul 2018 — Aug 2018 [monthly]

    Recruiting PHASE1

  17. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE1

  18. Feb 2018 — Jun 2018 [monthly]

    Recruiting PHASE1

  19. Jan 2018 — Feb 2018 [monthly]

    Recruiting PHASE1

  20. Feb 2017 — Jan 2018 [monthly]

    Recruiting PHASE1

  21. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE1

    First recorded

May 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Battle for a Cure Foundation
  • Cannonball Kids' Cancer Foundation
  • Eli Jackson Foundation
  • Eli's Block Party Childhood Cancer Foundation
  • Food and Drug Administration (FDA)
  • Gregory K. Friedman, MD
  • Hyundai Hope On Wheels
  • Jaxon's F.R.O.G. Foundation
  • Kaul Pediatric Research Institute
  • Kelsie's Crew
  • Memorial Sloan Kettering Cancer Center
  • National Center for Advancing Translational Sciences of the National Institutes of Health
  • Rally Foundation for Childhood Cancer Research
  • Sandcastle Kids
  • St. Baldrick's Foundation
  • The Andrew McDonough B+ Foundation
  • United States Department of Defense
  • University of Alabama at Birmingham
Data source: University of Alabama at Birmingham

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations