deltatrials
Terminated PHASE3 INTERVENTIONAL 2-arm NCT02467582

Adjuvant Aspirin Treatment for Colon Cancer Patients

Adjuvant Aspirin Treatment in PIK3CA Mutated Colon Cancer Patients. A Randomized, Double-blinded, Placebo-controlled, Phase III Trial

Sponsor: Central European Society for Anticancer Drug Research

Conditions Colon Cancer
Interventions Aspirin Placebo
Updated 27 times since 2017 Last updated: May 15, 2025 Started: Jun 9, 2016 Primary completion: Sep 14, 2023 Completion: Sep 14, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Board decision in 2020 due to lack of financial funding.

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A PHASE3 clinical study on Colon Cancer, this trial is terminated or withdrawn. The trial is conducted by Central European Society for Anticancer Drug Research and has accumulated 27 data snapshots since 2016. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~May 2017 · 4 months · monthly snapshot~May 2017 – ~Sep 2017 · 4 months · monthly snapshot~Sep 2017 – ~Jan 2018 · 4 months · monthly snapshot~Jan 2018 – ~Jun 2018 · 5 months · monthly snapshot~Jun 2018 – ~Aug 2018 · 2 months · monthly snapshot~Aug 2018 – ~Oct 2018 · 2 months · monthly snapshot~Oct 2018 – ~Dec 2018 · 2 months · monthly snapshot~Dec 2018 – ~Mar 2019 · 3 months · monthly snapshot~Mar 2019 – ~Aug 2019 · 5 months · monthly snapshot~Aug 2019 – ~Mar 2020 · 7 months · monthly snapshot~Mar 2020 – ~May 2020 · 2 months · monthly snapshot~May 2020 – ~Jun 2020 · 31 days · monthly snapshot~Jun 2020 – ~Oct 2020 · 4 months · monthly snapshot~Oct 2020 – ~Jan 2021 · 3 months · monthly snapshot~Jan 2021 – ~Oct 2021 · 9 months · monthly snapshot~Oct 2021 – ~Feb 2022 · 4 months · monthly snapshot~Feb 2022 – ~Mar 2022 · 28 days · monthly snapshot~Mar 2022 – ~Apr 2022 · 31 days · monthly snapshot~Apr 2022 – ~Feb 2023 · 10 months · monthly snapshot~Feb 2023 – ~Feb 2024 · 12 months · monthly snapshot~Feb 2024 – ~Jul 2024 · 5 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Dec 2024 · 3 months · monthly snapshot~Dec 2024 – ~Jun 2025 · 6 months · monthly snapshot~Jun 2025 – ~Aug 2025 · 2 months · monthly snapshot~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

27 versions recorded

  1. Sep 2025 — Present [monthly]

    Terminated PHASE3

  2. Aug 2025 — Sep 2025 [monthly]

    Terminated PHASE3

  3. Jun 2025 — Aug 2025 [monthly]

    Terminated PHASE3

    Status: Completed → Terminated

  4. Dec 2024 — Jun 2025 [monthly]

    Completed PHASE3

    Status: Active Not Recruiting → Completed

  5. Sep 2024 — Dec 2024 [monthly]

    Active Not Recruiting PHASE3

▶ Show 22 earlier versions

  1. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE3

  2. Feb 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE3

  3. Feb 2023 — Feb 2024 [monthly]

    Active Not Recruiting PHASE3

  4. Apr 2022 — Feb 2023 [monthly]

    Active Not Recruiting PHASE3

  5. Mar 2022 — Apr 2022 [monthly]

    Active Not Recruiting PHASE3

  6. Feb 2022 — Mar 2022 [monthly]

    Active Not Recruiting PHASE3

  7. Oct 2021 — Feb 2022 [monthly]

    Active Not Recruiting PHASE3

    Status: Recruiting → Active Not Recruiting

  8. Jan 2021 — Oct 2021 [monthly]

    Recruiting PHASE3

  9. Oct 2020 — Jan 2021 [monthly]

    Recruiting PHASE3

  10. Jun 2020 — Oct 2020 [monthly]

    Recruiting PHASE3

  11. May 2020 — Jun 2020 [monthly]

    Recruiting PHASE3

  12. Mar 2020 — May 2020 [monthly]

    Recruiting PHASE3

  13. Aug 2019 — Mar 2020 [monthly]

    Recruiting PHASE3

  14. Mar 2019 — Aug 2019 [monthly]

    Recruiting PHASE3

  15. Dec 2018 — Mar 2019 [monthly]

    Recruiting PHASE3

  16. Oct 2018 — Dec 2018 [monthly]

    Recruiting PHASE3

  17. Aug 2018 — Oct 2018 [monthly]

    Recruiting PHASE3

  18. Jun 2018 — Aug 2018 [monthly]

    Recruiting PHASE3

  19. Jan 2018 — Jun 2018 [monthly]

    Recruiting PHASE3

  20. Sep 2017 — Jan 2018 [monthly]

    Recruiting PHASE3

  21. May 2017 — Sep 2017 [monthly]

    Recruiting PHASE3

  22. Jan 2017 — May 2017 [monthly]

    Recruiting PHASE3

    First recorded

Jun 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Central European Society for Anticancer Drug Research
  • European Organisation for Research and Treatment of Cancer - EORTC
  • Swiss Cancer Institute
Data source: Swiss Cancer Institute

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Aarau, Switzerland , Baden, Switzerland , Basel, Switzerland , Bellinzona, Switzerland , Berlin, Germany , Bern, Switzerland , Biel, Switzerland , Brig, Switzerland , Bruchsal, Germany , Brussels, Belgium and 43 more locations