deltatrials
Completed EARLY_PHASE1 INTERVENTIONAL 1-arm NCT02467738

Surgical Resection and Intraoperative Cesium-131 Brachytherapy for Head and Neck Cancer

A Pilot Study Using Surgical Resection and Intraoperative Cesium-131 Permanent Interstitial Brachytherapy Implant in Resectable Recurrent Head and Neck Cancer

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University

Conditions Recurrent Head and Neck Carcinoma
Interventions Brachytherapy Cesium-131 Conventional surgery
Updated 16 times since 2017 Last updated: Sep 15, 2025 Started: Mar 17, 2015 Primary completion: May 28, 2020 Completion: May 28, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A EARLY_PHASE1 clinical study on Recurrent Head and Neck Carcinoma, this trial is completed. The trial is conducted by Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University and has accumulated 16 data snapshots since 2015. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Nov 2017 · 9 months · monthly snapshot~Nov 2017 – ~Mar 2018 · 4 months · monthly snapshot~Mar 2018 – ~Jun 2018 · 3 months · monthly snapshot~Jun 2018 – ~Sep 2018 · 3 months · monthly snapshot~Sep 2018 – ~Sep 2019 · 12 months · monthly snapshot~Sep 2019 – ~Dec 2019 · 3 months · monthly snapshot~Dec 2019 – ~Jan 2021 · 13 months · monthly snapshot~Jan 2021 – ~Jan 2023 · 24 months · monthly snapshot~Jan 2023 – ~Aug 2023 · 7 months · monthly snapshot~Aug 2023 – ~Jul 2024 · 11 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Jun 2025 · 9 months · monthly snapshot~Jun 2025 – ~Oct 2025 · 4 months · monthly snapshot~Oct 2025 – ~Feb 2026 · 4 months · monthly snapshot~Feb 2026 – present · 5 months · monthly snapshot

Change History

16 versions recorded

  1. Feb 2026 — Present [monthly]

    Completed EARLY_PHASE1

  2. Oct 2025 — Feb 2026 [monthly]

    Completed EARLY_PHASE1

  3. Jun 2025 — Oct 2025 [monthly]

    Completed EARLY_PHASE1

  4. Sep 2024 — Jun 2025 [monthly]

    Completed EARLY_PHASE1

  5. Jul 2024 — Sep 2024 [monthly]

    Completed EARLY_PHASE1

▶ Show 11 earlier versions

  1. Aug 2023 — Jul 2024 [monthly]

    Completed EARLY_PHASE1

    Status: Unknown Status → Completed

  2. Jan 2023 — Aug 2023 [monthly]

    Unknown Status EARLY_PHASE1

    Status: Active Not Recruiting → Unknown Status

  3. Jan 2021 — Jan 2023 [monthly]

    Active Not Recruiting EARLY_PHASE1

  4. Dec 2019 — Jan 2021 [monthly]

    Active Not Recruiting EARLY_PHASE1

  5. Sep 2019 — Dec 2019 [monthly]

    Active Not Recruiting EARLY_PHASE1

  6. Sep 2018 — Sep 2019 [monthly]

    Active Not Recruiting EARLY_PHASE1

    Status: Recruiting → Active Not Recruiting

  7. Jun 2018 — Sep 2018 [monthly]

    Recruiting EARLY_PHASE1

  8. Mar 2018 — Jun 2018 [monthly]

    Recruiting EARLY_PHASE1

  9. Nov 2017 — Mar 2018 [monthly]

    Recruiting EARLY_PHASE1

    Phase: NA → EARLY_PHASE1

  10. Feb 2017 — Nov 2017 [monthly]

    Recruiting NA

  11. Jan 2017 — Feb 2017 [monthly]

    Recruiting NA

    First recorded

Mar 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Data source: Thomas Jefferson University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations