deltatrials
Unknown PHASE2 INTERVENTIONAL 1-arm NCT02471391

ABT-199 & Ibrutinib in Mantle Cell Lymphoma (AIM) (AIM)

A Phase 2 Study of ABT-199 in Combination With Ibrutinib in the Treatment of Patients With Relapsed or Refractory Mantle Cell Lymphoma (AIM Study)

Sponsor: Peter MacCallum Cancer Centre, Australia

Conditions Mantle Cell Lymphoma
Interventions ABT-199 Ibrutinib
Updated 10 times since 2017 Last updated: Aug 17, 2023 Started: Jul 22, 2015 Primary completion: Nov 20, 2020 Completion: Jun 30, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Mantle Cell Lymphoma and is currently ongoing. Peter MacCallum Cancer Centre, Australia leads this study, which shows 10 recorded versions since 2015 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jan 2017 – ~Jun 2018 · 17 months · monthly snapshotRecruiting~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshotRecruiting~Jul 2018 – ~Jan 2021 · 30 months · monthly snapshotUnknown Status~Jan 2021 – ~Jun 2022 · 17 months · monthly snapshotUnknown Status~Jun 2022 – ~Apr 2023 · 10 months · monthly snapshotActive Not Recruiting~Apr 2023 – ~Sep 2023 · 5 months · monthly snapshotActive Not Recruiting~Sep 2023 – ~Jul 2024 · 10 months · monthly snapshotActive Not Recruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotActive Not Recruiting~Sep 2024 – ~Oct 2025 · 13 months · monthly snapshotActive Not Recruiting~Oct 2025 – present · 9 months · monthly snapshotUnknown

Change History

10 versions recorded

  1. Oct 2025 — Present [monthly]

    Unknown PHASE2

    Status: Active Not Recruiting → Unknown

  2. Sep 2024 — Oct 2025 [monthly]

    Active Not Recruiting PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE2

  4. Sep 2023 — Jul 2024 [monthly]

    Active Not Recruiting PHASE2

  5. Apr 2023 — Sep 2023 [monthly]

    Active Not Recruiting PHASE2

▶ Show 5 earlier versions

  1. Jun 2022 — Apr 2023 [monthly]

    Active Not Recruiting PHASE2

    Status: Unknown Status → Active Not Recruiting

  2. Jan 2021 — Jun 2022 [monthly]

    Unknown Status PHASE2

  3. Jul 2018 — Jan 2021 [monthly]

    Unknown Status PHASE2

    Status: Recruiting → Unknown Status

  4. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE2

  5. Jan 2017 — Jun 2018 [monthly]

    Recruiting PHASE2

    First recorded

Jul 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Peter MacCallum Cancer Centre, Australia
Data source: Peter MacCallum Cancer Centre, Australia

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations