deltatrials
Completed PHASE1 INTERVENTIONAL 1-arm NCT02478281

Safety, Tolerability, and Pharmacokinetic Study of Methylene Blue Following a 1 mg/kg Intravenous Dose in Healthy Adults

A One-Period, Single-Dose, Safety, Tolerability, and Pharmacokinetic Study of Methylene Blue Injection United States Pharmacopeia (USP) Following a 1 mg/kg Intravenous Dose in Healthy Adult Volunteers

Sponsor: American Regent, Inc.

Interventions Methylene Blue
Updated 8 times since 2017 Last updated: Jun 3, 2025 Started: Oct 31, 2012 Primary completion: Oct 31, 2012 Completion: Mar 31, 2013
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02478281, this PHASE1 trial focuses on Congenital Methemoglobinemia and Methemoglobinemia and remains completed. Sponsored by American Regent, Inc., it has been updated 8 times since 2012, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotCompleted~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshotCompleted~Jun 2018 – ~Feb 2019 · 8 months · monthly snapshotCompleted~Feb 2019 – ~Jan 2021 · 23 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Jul 2025 · 10 months · monthly snapshotCompleted~Jul 2025 – present · 12 months · monthly snapshotCompleted

Change History

8 versions recorded
  1. Jul 2025 — Present [monthly]

    Completed PHASE1

  2. Sep 2024 — Jul 2025 [monthly]

    Completed PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  4. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE1

  5. Feb 2019 — Jan 2021 [monthly]

    Completed PHASE1

Show 3 earlier versions
  1. Jun 2018 — Feb 2019 [monthly]

    Completed PHASE1

  2. Feb 2017 — Jun 2018 [monthly]

    Completed PHASE1

  3. Jan 2017 — Feb 2017 [monthly]

    Completed PHASE1

    First recorded

Oct 2012

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • American Regent, Inc.
Data source: American Regent, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

No location information available.