deltatrials
Completed PHASE4 INTERVENTIONAL 2-arm NCT02478489

Alcohol Disorder hOsPital Treatment Trial (ADOPT)

Oral v. Injection Naltrexone in Hospital: Comparative Effectiveness for Alcoholism

Sponsor: Boston University

Conditions Alcohol Dependence Alcohol Use Disorder Heavy Drinking
Interventions Extended-release injectable naltrexone (XR-NTX) Oral naltrexone (PO-NTX)
Updated 17 times since 2017 Last updated: Jun 9, 2021 Started: Jun 30, 2016 Primary completion: Jul 31, 2020 Completion: Oct 31, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE4 trial investigates Alcohol Dependence and Alcohol Use Disorder and is currently completed. Boston University leads this study, which shows 17 recorded versions since 2016 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Mar 2018 · 14 months · monthly snapshot~Mar 2018 – ~Jun 2018 · 3 months · monthly snapshot~Jun 2018 – ~Apr 2019 · 10 months · monthly snapshot~Apr 2019 – ~Jun 2019 · 2 months · monthly snapshot~Jun 2019 – ~Oct 2019 · 4 months · monthly snapshot~Oct 2019 – ~Dec 2019 · 2 months · monthly snapshot~Dec 2019 – ~May 2020 · 5 months · monthly snapshot~May 2020 – ~Oct 2020 · 5 months · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Dec 2020 · 30 days · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshot~Sep 2021 – ~Dec 2022 · 15 months · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Jul 2024 · 18 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 22 months · monthly snapshot

Change History

17 versions recorded

  1. Sep 2024 — Present [monthly]

    Completed PHASE4

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE4

  3. Jan 2023 — Jul 2024 [monthly]

    Completed PHASE4

  4. Dec 2022 — Jan 2023 [monthly]

    Completed PHASE4

  5. Sep 2021 — Dec 2022 [monthly]

    Completed PHASE4

▶ Show 12 earlier versions

  1. Jan 2021 — Sep 2021 [monthly]

    Completed PHASE4

  2. Dec 2020 — Jan 2021 [monthly]

    Completed PHASE4

    Status: Active Not Recruiting → Completed

  3. Nov 2020 — Dec 2020 [monthly]

    Active Not Recruiting PHASE4

  4. Oct 2020 — Nov 2020 [monthly]

    Active Not Recruiting PHASE4

  5. May 2020 — Oct 2020 [monthly]

    Active Not Recruiting PHASE4

    Status: Enrolling By Invitation → Active Not Recruiting

  6. Dec 2019 — May 2020 [monthly]

    Enrolling By Invitation PHASE4

  7. Oct 2019 — Dec 2019 [monthly]

    Enrolling By Invitation PHASE4

  8. Jun 2019 — Oct 2019 [monthly]

    Enrolling By Invitation PHASE4

  9. Apr 2019 — Jun 2019 [monthly]

    Enrolling By Invitation PHASE4

  10. Jun 2018 — Apr 2019 [monthly]

    Enrolling By Invitation PHASE4

  11. Mar 2018 — Jun 2018 [monthly]

    Enrolling By Invitation PHASE4

  12. Jan 2017 — Mar 2018 [monthly]

    Enrolling By Invitation PHASE4

    First recorded

Jun 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Boston University
  • National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Data source: Boston University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations