Couples-Based Yoga Program in Improving Quality of Life in Patients With High-Grade Glioma Undergoing Radiation Therapy and Their Partners
Couple-Based Yoga Program for Glioma Patients and Their Partners
Sponsor: M.D. Anderson Cancer Center
A observational or N/A phase clinical study on Caregiver and Glioma, this trial is ongoing. The trial is conducted by M.D. Anderson Cancer Center and has accumulated 23 data snapshots since 2015. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.
Study Description(click to expand)PRIMARY OBJECTIVES: I. Examine the feasibility of a couple-based and a caregiver yoga program in glioma patients undergoing radiotherapy (RT) and their partners. SECONDARY OBJECTIVES: I. Establish the initial efficacy of the yoga program in patients and their partners regarding quality of life (QOL) outcomes (i.e., fatigue, sleep disturbance, depressive symptoms, and overall QOL and health care utilization). EXPLORATORY OBJECTIVES: I. Explore potential moderation (e.g., baseline psychological distress, patients' tumor grade, performance status and class attendance) of the intervention effects. OUTLINE: The first five couples are assigned to arm I. All subsequent couples are randomized to 1 of 2 arms. ARM I: Patients and their partners attend up to 15, 45-60 minute sessions of Hatha yoga over the course of radiation therapy 5 times a week for 5-6 weeks. The program comprises four main components: joint loosening with breath synchronization; postures with deep relaxation techniques; breath energization with sound resonance; and meditation. At the fifth session, patients and their partners receive a digital video disc (DVD) and are encouraged to practice on their own (individually and/or together) on the days when they do not meet with the instructor. ARM II: Patients receive standard of care provided by the health care...
PRIMARY OBJECTIVES:
I. Examine the feasibility of a couple-based and a caregiver yoga program in glioma patients undergoing radiotherapy (RT) and their partners.
SECONDARY OBJECTIVES:
I. Establish the initial efficacy of the yoga program in patients and their partners regarding quality of life (QOL) outcomes (i.e., fatigue, sleep disturbance, depressive symptoms, and overall QOL and health care utilization).
EXPLORATORY OBJECTIVES:
I. Explore potential moderation (e.g., baseline psychological distress, patients' tumor grade, performance status and class attendance) of the intervention effects.
OUTLINE: The first five couples are assigned to arm I. All subsequent couples are randomized to 1 of 2 arms.
ARM I: Patients and their partners attend up to 15, 45-60 minute sessions of Hatha yoga over the course of radiation therapy 5 times a week for 5-6 weeks. The program comprises four main components: joint loosening with breath synchronization; postures with deep relaxation techniques; breath energization with sound resonance; and meditation. At the fifth session, patients and their partners receive a digital video disc (DVD) and are encouraged to practice on their own (individually and/or together) on the days when they do not meet with the instructor.
ARM II: Patients receive standard of care provided by the health care team and complete questionnaires before and after radiation therapy.
Status Flow
Change History
23 versions recorded-
Apr 16, 2026 — Present [daily]
Active Not Recruiting
Phase: NA → None
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Nov 2025 — Apr 2026 [monthly]
Active Not Recruiting NA
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May 2025 — Nov 2025 [monthly]
Active Not Recruiting NA
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Nov 2024 — May 2025 [monthly]
Active Not Recruiting NA
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Sep 2024 — Nov 2024 [monthly]
Active Not Recruiting NA
▶ Show 18 earlier versions
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Jul 2024 — Sep 2024 [monthly]
Active Not Recruiting NA
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May 2024 — Jul 2024 [monthly]
Active Not Recruiting NA
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Nov 2023 — May 2024 [monthly]
Active Not Recruiting NA
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May 2023 — Nov 2023 [monthly]
Active Not Recruiting NA
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Mar 2023 — May 2023 [monthly]
Active Not Recruiting NA
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Sep 2022 — Mar 2023 [monthly]
Active Not Recruiting NA
Status: Recruiting → Active Not Recruiting
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Jan 2021 — Sep 2022 [monthly]
Recruiting NA
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Dec 2020 — Jan 2021 [monthly]
Recruiting NA
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Aug 2020 — Dec 2020 [monthly]
Recruiting NA
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Aug 2019 — Aug 2020 [monthly]
Recruiting NA
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Jun 2019 — Aug 2019 [monthly]
Recruiting NA
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Dec 2018 — Jun 2019 [monthly]
Recruiting NA
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Nov 2018 — Dec 2018 [monthly]
Recruiting NA
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Sep 2018 — Nov 2018 [monthly]
Recruiting NA
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Jun 2018 — Sep 2018 [monthly]
Recruiting NA
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Jan 2018 — Jun 2018 [monthly]
Recruiting NA
Status: Active Not Recruiting → Recruiting
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Aug 2017 — Jan 2018 [monthly]
Active Not Recruiting NA
Status: Recruiting → Active Not Recruiting
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Jan 2017 — Aug 2017 [monthly]
Recruiting NA
First recorded
Jun 2015
Trial started
Per CT.gov start date — pre-dates our first snapshot
Eligibility Summary
This randomized clinical trial studies couples-based yoga program in improving quality of life in patients with high-grade glioma undergoing radiation therapy and their partners. A couple-based Hatha yoga program may improve fatigue, distress, sleep quality, and overall quality of life in patients with glioma and their partners.
Contact Information
- M.D. Anderson Cancer Center
- National Cancer Institute (NCI)
For direct contact, visit the study record on ClinicalTrials.gov .