An Investigational Immuno-therapy Study to Investigate the Safety and Effectiveness of Nivolumab, and Nivolumab Combination Therapy in Virus-associated Tumors (CheckMate358)
Non-Comparative, Open-Label, Multiple Cohort, Phase 1/2 Study of Nivolumab Monotherapy and Nivolumab Combination Therapy in Subjects With Virus-Positive and Virus-Negative Solid Tumors
Sponsor: Bristol-Myers Squibb
A PHASE1/PHASE2 clinical study on Various Advanced Cancer, this trial is completed. The trial is conducted by Bristol-Myers Squibb and has accumulated 31 data snapshots since 2015. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.
Status Flow
Change History
31 versions recorded-
Dec 2025 — Present [monthly]
Completed PHASE1/PHASE2
-
Sep 2025 — Dec 2025 [monthly]
Completed PHASE1/PHASE2
-
Sep 2024 — Sep 2025 [monthly]
Completed PHASE1/PHASE2
-
Jul 2024 — Sep 2024 [monthly]
Completed PHASE1/PHASE2
Phase: PHASE1_PHASE2 → PHASE1/PHASE2
-
Dec 2023 — Jul 2024 [monthly]
Completed PHASE1_PHASE2
▶ Show 26 earlier versions
-
Jan 2023 — Dec 2023 [monthly]
Completed PHASE1_PHASE2
Status: Active Not Recruiting → Completed
-
Sep 2022 — Jan 2023 [monthly]
Active Not Recruiting PHASE1_PHASE2
-
Jun 2022 — Sep 2022 [monthly]
Active Not Recruiting PHASE1_PHASE2
-
May 2022 — Jun 2022 [monthly]
Active Not Recruiting PHASE1_PHASE2
-
Mar 2022 — May 2022 [monthly]
Active Not Recruiting PHASE1_PHASE2
-
Feb 2022 — Mar 2022 [monthly]
Active Not Recruiting PHASE1_PHASE2
-
Dec 2021 — Feb 2022 [monthly]
Active Not Recruiting PHASE1_PHASE2
-
Jan 2021 — Dec 2021 [monthly]
Active Not Recruiting PHASE1_PHASE2
-
Oct 2020 — Jan 2021 [monthly]
Active Not Recruiting PHASE1_PHASE2
-
Aug 2020 — Oct 2020 [monthly]
Active Not Recruiting PHASE1_PHASE2
-
Jul 2020 — Aug 2020 [monthly]
Active Not Recruiting PHASE1_PHASE2
-
Jun 2020 — Jul 2020 [monthly]
Active Not Recruiting PHASE1_PHASE2
-
Apr 2020 — Jun 2020 [monthly]
Active Not Recruiting PHASE1_PHASE2
Status: Recruiting → Active Not Recruiting
-
Feb 2020 — Apr 2020 [monthly]
Recruiting PHASE1_PHASE2
-
Dec 2019 — Feb 2020 [monthly]
Recruiting PHASE1_PHASE2
-
Sep 2019 — Dec 2019 [monthly]
Recruiting PHASE1_PHASE2
-
May 2019 — Sep 2019 [monthly]
Recruiting PHASE1_PHASE2
-
Nov 2018 — May 2019 [monthly]
Recruiting PHASE1_PHASE2
-
Aug 2018 — Nov 2018 [monthly]
Recruiting PHASE1_PHASE2
-
Jun 2018 — Aug 2018 [monthly]
Recruiting PHASE1_PHASE2
-
Jul 2017 — Jun 2018 [monthly]
Recruiting PHASE1_PHASE2
-
May 2017 — Jul 2017 [monthly]
Recruiting PHASE1_PHASE2
-
Apr 2017 — May 2017 [monthly]
Recruiting PHASE1_PHASE2
-
Mar 2017 — Apr 2017 [monthly]
Recruiting PHASE1_PHASE2
-
Feb 2017 — Mar 2017 [monthly]
Recruiting PHASE1_PHASE2
-
Jan 2017 — Feb 2017 [monthly]
Recruiting PHASE1_PHASE2
First recorded
Oct 2015
Trial started
Per CT.gov start date — pre-dates our first snapshot
Eligibility Summary
No eligibility information available.
Contact Information
- Bristol-Myers Squibb
- Ono Pharmaceutical Co. Ltd
For direct contact, visit the study record on ClinicalTrials.gov .