deltatrials
Completed OBSERVATIONAL NCT02488863

NEPAL (Neuromodulatory Examination of Pain and Mobility Across the Lifespan) (NEPAL)

Neuroimaging Age-related Versus Pain-related Changes in Pain Modulation

Sponsor: National Institute on Aging (NIA)

Conditions Musculoskeletal Pain Pain, Chronic
Interventions MRI Neuroimaging Physical and Cognitive Function Testing Quantitative Sensory Testing Questionnaires
Updated 24 times since 2017 Last updated: Mar 11, 2025 Started: Jul 31, 2015 Primary completion: Feb 4, 2024 Completion: Feb 4, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This observational or N/A phase trial investigates Musculoskeletal Pain and Pain, Chronic and is currently completed. National Institute on Aging (NIA) leads this study, which shows 24 recorded versions since 2015 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Aug 2017 · 7 months · monthly snapshot~Aug 2017 – ~Sep 2017 · 31 days · monthly snapshot~Sep 2017 – ~Dec 2017 · 3 months · monthly snapshot~Dec 2017 – ~Feb 2018 · 2 months · monthly snapshot~Feb 2018 – ~Apr 2018 · 59 days · monthly snapshot~Apr 2018 – ~May 2018 · 30 days · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Nov 2018 · 5 months · monthly snapshot~Nov 2018 – ~Feb 2019 · 3 months · monthly snapshot~Feb 2019 – ~May 2019 · 3 months · monthly snapshot~May 2019 – ~Jul 2019 · 2 months · monthly snapshot~Jul 2019 – ~Mar 2020 · 8 months · monthly snapshot~Mar 2020 – ~Jun 2020 · 3 months · monthly snapshot~Jun 2020 – ~Nov 2020 · 5 months · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Apr 2021 · 3 months · monthly snapshot~Apr 2021 – ~Dec 2021 · 8 months · monthly snapshot~Dec 2021 – ~Jun 2022 · 6 months · monthly snapshot~Jun 2022 – ~May 2023 · 11 months · monthly snapshot~May 2023 – ~May 2024 · 12 months · monthly snapshot~May 2024 – ~Jul 2024 · 2 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Apr 2025 · 7 months · monthly snapshot~Apr 2025 – present · 15 months · monthly snapshot

Change History

24 versions recorded

  1. Apr 2025 — Present [monthly]

    Completed

  2. Sep 2024 — Apr 2025 [monthly]

    Completed

  3. Jul 2024 — Sep 2024 [monthly]

    Completed

  4. May 2024 — Jul 2024 [monthly]

    Completed

    Status: Active Not Recruiting → Completed

  5. May 2023 — May 2024 [monthly]

    Active Not Recruiting

    Status: Recruiting → Active Not Recruiting

▶ Show 19 earlier versions

  1. Jun 2022 — May 2023 [monthly]

    Recruiting

  2. Dec 2021 — Jun 2022 [monthly]

    Recruiting

  3. Apr 2021 — Dec 2021 [monthly]

    Recruiting

  4. Jan 2021 — Apr 2021 [monthly]

    Recruiting

  5. Nov 2020 — Jan 2021 [monthly]

    Recruiting

  6. Jun 2020 — Nov 2020 [monthly]

    Recruiting

  7. Mar 2020 — Jun 2020 [monthly]

    Recruiting

  8. Jul 2019 — Mar 2020 [monthly]

    Recruiting

  9. May 2019 — Jul 2019 [monthly]

    Recruiting

  10. Feb 2019 — May 2019 [monthly]

    Recruiting

  11. Nov 2018 — Feb 2019 [monthly]

    Recruiting

  12. Jun 2018 — Nov 2018 [monthly]

    Recruiting

  13. May 2018 — Jun 2018 [monthly]

    Recruiting

  14. Apr 2018 — May 2018 [monthly]

    Recruiting

    Phase: NA → None

  15. Feb 2018 — Apr 2018 [monthly]

    Recruiting NA

  16. Dec 2017 — Feb 2018 [monthly]

    Recruiting NA

  17. Sep 2017 — Dec 2017 [monthly]

    Recruiting NA

  18. Aug 2017 — Sep 2017 [monthly]

    Recruiting NA

  19. Jan 2017 — Aug 2017 [monthly]

    Recruiting NA

    First recorded

Jul 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Institute on Aging (NIA)
  • National Institutes of Health (NIH)
  • University of Florida
Data source: University of Florida

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations