deltatrials
Completed PHASE1 INTERVENTIONAL 1-arm NCT02493816

Safety Study of Gene-modified Autologous Fibroblasts in Recessive Dystrophic Epidermolysis Bullosa

Phase I Study of Lentiviral-mediated COL7A1 Gene-modified Autologous Fibroblasts in Adults With Recessive Dystrophic Epidermolysis Bullosa.

Sponsor: King's College London

Updated 8 times since 2017 Last updated: Sep 20, 2019 Started: Sep 30, 2015 Primary completion: Mar 31, 2018 Completion: Mar 31, 2018
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Recessive Dystrophic Epidermolysis Bullosa and is currently completed. King's College London leads this study, which shows 8 recorded versions since 2015 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Feb 2018 · 13 months · monthly snapshotRecruiting~Feb 2018 – ~Jun 2018 · 4 months · monthly snapshotActive Not Recruiting~Jun 2018 – ~Sep 2018 · 3 months · monthly snapshotActive Not Recruiting~Sep 2018 – ~Oct 2019 · 13 months · monthly snapshotCompleted~Oct 2019 – ~Jan 2021 · 15 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 24 months · monthly snapshotCompleted

Change History

8 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  3. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE1

  4. Oct 2019 — Jan 2021 [monthly]

    Completed PHASE1

  5. Sep 2018 — Oct 2019 [monthly]

    Completed PHASE1

    Status: Active Not RecruitingCompleted

Show 3 earlier versions
  1. Jun 2018 — Sep 2018 [monthly]

    Active Not Recruiting PHASE1

  2. Feb 2018 — Jun 2018 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  3. Jan 2017 — Feb 2018 [monthly]

    Recruiting PHASE1

    First recorded

Sep 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • King's College London
  • University College, London
Data source: King's College London

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations