deltatrials
Unknown PHASE2 INTERVENTIONAL 1-arm NCT02501551

Regorafenib, C-kit Mutated Malignant Melanoma, 2nd Line Therapy

A Phase II Study to Evaluate the Efficacy of Regorafenib in C-kit Mutated Metastatic Malignant Melanoma Failed First-Line Dacarbazine, Temozolomide or Immune Therapy

Sponsor: Yonsei University

Conditions Melanoma
Interventions regorafenib
Updated 10 times since 2017 Last updated: Apr 1, 2021 Started: Feb 28, 2015 Primary completion: May 31, 2022 Completion: Jun 30, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Melanoma, this trial is ongoing. The trial is conducted by Yonsei University and has accumulated 10 data snapshots since 2015. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Jun 2018 · 17 months · monthly snapshotRecruiting~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshotRecruiting~Jul 2018 – ~Feb 2020 · 19 months · monthly snapshotRecruiting~Feb 2020 – ~Jan 2021 · 11 months · monthly snapshotRecruiting~Jan 2021 – ~May 2021 · 4 months · monthly snapshotRecruiting~May 2021 – ~May 2023 · 24 months · monthly snapshotRecruiting~May 2023 – ~Jul 2024 · 14 months · monthly snapshotUnknown Status~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotUnknown~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotUnknown~Sep 2025 – present · 10 months · monthly snapshotUnknown

Change History

10 versions recorded
  1. Sep 2025 — Present [monthly]

    Unknown PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Unknown PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Unknown PHASE2

    Status: Unknown StatusUnknown

  4. May 2023 — Jul 2024 [monthly]

    Unknown Status PHASE2

    Status: RecruitingUnknown Status

  5. May 2021 — May 2023 [monthly]

    Recruiting PHASE2

Show 5 earlier versions
  1. Jan 2021 — May 2021 [monthly]

    Recruiting PHASE2

  2. Feb 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

  3. Jul 2018 — Feb 2020 [monthly]

    Recruiting PHASE2

  4. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE2

  5. Jan 2017 — Jun 2018 [monthly]

    Recruiting PHASE2

    First recorded

Feb 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Yonsei University
Data source: Yonsei University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations